Rat Anti-IL-17E Monoclonal Antibody – Cat# MBS690084

IL-17E Antibody – Rat Monoclonal

Name: IL-17E Antibody; Monoclonal; Rat; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS690084
Price: 875 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS690084

The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

IL-17E, Monoclonal Antibody

Full Product Name

Rat Anti-Mouse IL-17E

Product Gene Name

anti-IL-17E antibody

Product Synonym Names

Il25; Il17e; IL-17e

Clonality

Monoclonal

Isotype

IgG2

Clone Number

(5J46)

Host

Rat

Species Reactivity

Mouse

Form/Format

Lyophilized

Preparation and Storage

Lyophilized samples are stable for 2 years from date of receipt when stored at -70 degree C. Reconstituted antibody can be aliquoted and stored frozen at < -20 degree C for at least for six months without detectable loss of activity.

Molecular Weight

19,210 Da

Chromosome Location

Chromosome: 14; NC_000080.6 (54929394..54935841). Location: 14 C3; 14

3D Structure

ModBase 3D Structure for Q8VHH8

Antibody Generation

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of IL-17E.

Reconstitution

Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml.

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-IL-17E antibody

Western Blot (WB)

Other Notes

Small volumes of anti-IL-17E antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL-17E purchase

MBS690084 is an antibody targeting IL-17E. Also known as Rat Anti-Mouse IL-17E. Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-17E. It may not necessarily be applicable to this product.

NCBI GI #

18141561

NCBI GeneID

140806

NCBI Accession #

NP_542767.1

UniProt Primary Accession #

Q8VHH8

GenBank Nucleotide #

NM_080729.3

NCBI Official Full Name

interleukin-25

NCBI Official Synonym Full Names

interleukin 25

NCBI Official Symbol

Il25

NCBI Official Synonym Symbols

Il17e; IL-17e

UniProt Protein Name

IL25

Protein Family

Interleukin

UniProt Gene Name

Il25

UniProt Synonym Gene Names

Il17e

UniProt Entry Name

Q8VHH8_MOUSE

NCBI Protein Information

interleukin-25; interleukin 17E

UniProt Comments for IL-17E

IL25: Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses. Belongs to the IL-17 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Molecular Function: cytokine activity; interleukin-17E receptor binding

Biological Process: response to fungus; inflammatory response to antigenic stimulus; response to nematode; eosinophil differentiation; positive regulation of transcription from RNA polymerase II promoter; inflammatory response

Research Articles on IL-17E

1. IL-25 expression is markedly reduced during human and experimental fulminant hepatitis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-IL-17E antibody

Products by Pathway	Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram

Diseases associated with anti-IL-17E antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>28 publications with IL-17E and Inflammation
Hypersensitivity Antibodies	>24 publications with IL-17E and Hypersensitivity
Lung Diseases Antibodies	>12 publications with IL-17E and Lung Diseases
Skin Diseases Antibodies	>8 publications with IL-17E and Skin Diseases
Hyperplasia Antibodies	>7 publications with IL-17E and Hyperplasia
Disease Models, Animal Antibodies	>5 publications with IL-17E and Disease Models, Animal
Colitis Antibodies	>4 publications with IL-17E and Colitis
Necrosis Antibodies	>4 publications with IL-17E and Necrosis
Pneumonia Antibodies	>2 publications with IL-17E and Pneumonia
Leukocytosis Antibodies	>1 publications with IL-17E and Leukocytosis

Organs/Tissues associated with anti-IL-17E antibody

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>1 publications with IL-17E and Embryonic Tissue