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IL-17B receptor Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS690280

IL-17B receptor (IL-17B R), also known as IL-17Rh1, IL-17ER and EVI27, is a 502 amino acid (aa) type I membrane protein with a 17 aa signal peptide, a 275 aa extracellular domain, a 21 aa transmembrane domain and a 189 aa cytoplasmic tail. By alternative… More details

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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
IL-17B receptor, Monoclonal Antibody
Full Product Name
Rat Anti-Mouse IL-17B receptor
Product Synonym Names
Anti-mouse Interleukin-17B Receptor [IL-17B R] (#9J28)
Clonality
Monoclonal
Isotype
IgG2
Clone Number
(5P14)
Host
Rat
Species Reactivity
Mouse
Form/Format
The IgG fraction of culture supernatant was purified by Protein A/G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS). Lyophilized samples are stable for 2 years from date of receipt when stored at
Purity/Purification
Protein A/G affinity chromatography
Specificity
This antibody detects mouse IL-17B R in Western blotting, but not mouse IL-17 R.
Preparation and Storage
Lyophilized samples are stable for 2 years from date of receipt when stored at -70 degree C. Reconstituted antibody can be aliquoted and stored frozen at < -20 degree C for at least for six months without detectable loss of activity.
Molecular Weight
55,617 Da
Chromosome Location
Chromosome: 14; NC_000080.6 (29995506..30008896, complement). Location: 14 B; 14 18.39 cM
3D Structure
ModBase 3D Structure for Q9JIP3
Antibody Generation
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant protein of IL-17B R extracellular domain. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography.
Reconstitution
Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-IL-17B receptor antibody
Western Blot (WB), Neutr
Application Notes for anti-IL-17B receptor antibody
1. Western blot: Yes (1:500-1000)

Other Notes

Small volumes of anti-IL-17B receptor antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL-17B receptor purchase

MBS690280 is an antibody targeting IL-17B receptor. Also known as Rat Anti-Mouse IL-17B receptor. Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-17B receptor. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-17 receptor B
NCBI Official Synonym Full Names
interleukin 17 receptor B
NCBI Official Symbol
Il17rb
NCBI Official Synonym Symbols
Evi27; Il17br; IL-17ER; IL17RH1; IL-17Rh1
UniProt Protein Name
Interleukin-17 receptor B
UniProt Synonym Protein Names
IL-17 receptor homolog 1; IL-17ER; IL-17Rh1; IL17Rh1; Interleukin-17B receptor
UniProt Gene Name
Il17rb
UniProt Synonym Gene Names
Evi27; Il17br; IL-17 receptor B; IL-17RB; IL-17ER; IL-17Rh1; IL17Rh1
UniProt Entry Name
I17RB_MOUSE
NCBI Protein Information
interleukin-17 receptor B; IL-17RB; IL-17B receptor; IL-17 receptor B; IL-17 receptor homolog 1; interleukin 17B receptor; interleukin-17B receptor; ecotropic viral integration site 27

UniProt Comments for IL-17B receptor

Function: Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.

Subunit structure: Interacts with DAZAP2

By similarity.

Subcellular location: Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted.

Tissue specificity: Liver and testis. Expressed at lower level in kidney and lung. Expressed in selected T-cell, B-cell and myeloid cell lines.

Miscellaneous: Evi27 is a common site of retroviral integration in Bxh2 murine myeloid leukemias, localized near the Il17rb gene. Proviral integrations result in increased expression of Il17rb on the cell surface.

Sequence similarities: Contains 1 SEFIR domain.
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Precautions

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Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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