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Carboxypeptidase A2 (CPA2) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS690395

Carboxypeptidase A2 encoded by the CPA2 gene cleaves the Cterminal amide or ester bond of peptides that have a free C terminal carboxyl group. It prefers the C terminal residues with aromatic side chains including Phe, Tyr, and Trp. The deduced amino acid… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
Carboxypeptidase A2 (CPA2), Monoclonal Antibody
Full Product Name
Mouse Anti-Human Carboxypeptidase A2
Product Gene Name
Product Synonym Names
CPA2
Clonality
Monoclonal
Isotype
IgG2
Clone Number
(11M21)
Host
Mouse
Species Reactivity
Human
Form/Format
Lyophilized
Preparation and Storage
Lyophilized samples are stable for 2 years from date of receipt when stored at -70 degree C. Reconstituted antibody can be aliquoted and stored frozen at < -20 degree C for at least for six months without detectable loss of activity.
Molecular Weight
47,030 Da
Chromosome Location
Chromosome: 7; NC_000007.14 (130266863..130289798). Location: 7q32
OMIM
600688
3D Structure
ModBase 3D Structure for P48052
Antibody Generation
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Carboxypeptidase A2.
Reconstitution
Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-CPA2 antibody
Western Blot (WB), Neutr

Other Notes

Small volumes of anti-CPA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CPA2 purchase

MBS690395 is an antibody targeting CPA2. Also known as Mouse Anti-Human Carboxypeptidase A2. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CPA2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
carboxypeptidase A2
NCBI Official Synonym Full Names
carboxypeptidase A2 (pancreatic)
NCBI Official Symbol
CPA2
UniProt Protein Name
Carboxypeptidase A2
UniProt Gene Name
CPA2
UniProt Entry Name
CBPA2_HUMAN
NCBI Protein Information
carboxypeptidase A2

NCBI Summary for CPA2

Three different forms of human pancreatic procarboxypeptidase A have been isolated. The encoded protein represents the A2 form, which is a monomeric protein with different biochemical properties from the A1 and A3 forms. The A2 form of pancreatic procarboxypeptidase acts on aromatic C-terminal residues and is a secreted protein. [provided by RefSeq, Dec 2008]
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UniProt Comments for CPA2

Catalytic activity: Similar to that of carboxypeptidase A (EC 3.4.17.1), but with a preference for bulkier C-terminal residues.

Cofactor: Binds 1 zinc ion per subunit.

Subcellular location: Secreted.

Sequence similarities: Belongs to the peptidase M14 family.

Sequence caution: The sequence AAA74425.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAH07009.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAH14571.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAH15140.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence EAL24092.1 differs from that shown. Reason: Erroneous gene model prediction.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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