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IL-17B receptor Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS690413

IL-17B receptor (IL-17B R), also known as IL-17Rh1, IL-17ER and EVI27, is a 502 amino acid (aa) type I membrane protein with a 17 aa signal peptide, a 275 aa extracellular domain, a 21 aa transmembrane domain and a 189 aa cytoplasmic tail. By alternative… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
IL-17B receptor, Monoclonal Antibody
Full Product Name
Mouse Anti-Human IL-17B receptor
Product Synonym Names
IL17RB; CRL4; EVI27; IL17BR; IL17RH1
Clonality
Monoclonal
Isotype
IgG2
Clone Number
(9J28)
Host
Mouse
Species Reactivity
Human
Form/Format
Lyophilized
Purity/Purification
Protein G chromatography
Preparation and Storage
Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least for six months without detectable loss of activity.

Ships in blue ice.
Molecular Weight
55,885 Da
Chromosome Location
Chromosome: 3; NC_000003.12 (53846550..53865800). Location: 3p21.1
OMIM
605458
3D Structure
ModBase 3D Structure for Q9NRM6
Antigen
Human Recombinant IL-17B R EC domain.
Preparation
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of IL-17B R extracellular domain.
Reconsitution buffer
PBS (sterile)
Reconstitution
Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml.
Remarks
This antibody was selected for its ability to detect human IL-18B R
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-IL-17B receptor antibody
WB, N
Application Notes for anti-IL-17B receptor antibody
Western Blot: 1:500-1:1000

Neutralization of IL-17B-receptor bioactivity: Yes

Other Notes

Small volumes of anti-IL-17B receptor antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL-17B receptor purchase

MBS690413 is an antibody targeting IL-17B receptor. Also known as Mouse Anti-Human IL-17B receptor. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-17B receptor. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-17 receptor B
NCBI Official Synonym Full Names
interleukin 17 receptor B
NCBI Official Symbol
IL17RB
NCBI Official Synonym Symbols
CRL4; EVI27; IL17BR; IL17RH1
UniProt Protein Name
Interleukin-17 receptor B
UniProt Synonym Protein Names
Cytokine receptor-like 4; IL-17 receptor homolog 1; IL-17Rh1; IL17Rh1; Interleukin-17B receptor
UniProt Gene Name
IL17RB
UniProt Synonym Gene Names
CRL4; EVI27; IL17BR; IL-17 receptor B; IL-17RB; IL-17Rh1; IL17Rh1
UniProt Entry Name
I17RB_HUMAN
NCBI Protein Information
interleukin-17 receptor B; IL-17RB; IL-17Rh1; IL-17B receptor; IL-17 receptor B; cytokine receptor CRL4; IL-17 receptor homolog 1; cytokine receptor-like 4; interleukin 17B receptor; interleukin-17B receptor; interleukin 17 receptor homolog 1

NCBI Summary for IL-17B receptor

The protein encoded by this gene is a cytokine receptor. This receptor specifically binds to IL17B and IL17E, but does not bind to IL17 and IL17C. This receptor has been shown to mediate the activation of NF-kappaB and the production of IL8 induced by IL17E. The expression of the rat counterpart of this gene was found to be significantly up-regulated during intestinal inflammation, which suggested the immunoregulatory activity of this receptor. [provided by RefSeq, Jul 2008]
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UniProt Comments for IL-17B receptor

Function: Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells. Ref.8

Subunit structure: Interacts with DAZAP2. Ref.10

Subcellular location: Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted.

Tissue specificity: Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines.

Sequence similarities: Contains 1 SEFIR domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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