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IL-10 receptor alpha Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS690469

Human and mouse IL-10 receptors are structurally related to the IFN-gamma receptor. These receptors are members of the class II subgroup of the cytokine receptor superfamily. The deduced amino acid sequence of human IL-10 R is approximately 60% identical to… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
IL-10 receptor alpha, Monoclonal Antibody
Full Product Name
Rat Anti-Mouse IL-10 receptor alpha
Product Synonym Names
Anti-mouse Interleukin-10 Receptor alpha [IL-10Ralpha] (#9E12)
Clonality
Monoclonal
Isotype
IgG
Clone Number
9E12
Host
Rat
Species Reactivity
Mouse
Form/Format
The IgG fraction of culture supernatant was purified by Protein A/G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS). Lyophilized samples are stable for 2 years from date of receipt when stored at
Purity/Purification
Protein A/G affinity chromatography
Specificity
This antibody detects mouse IL-10Ralpha in Western blotting.
Preparation and Storage
Lyophilized samples are stable for 2 years from date of receipt when stored at -70 degree C. Reconstituted antibody can be aliquoted and stored frozen at < -20 degree C for at least for six months without detectable loss of activity.
Molecular Weight
64,248 Da
Chromosome Location
Chromosome: 9; NC_000075.6 (45253839..45269146, complement). Location: 9 A5.2; 9 24.84 cM
3D Structure
ModBase 3D Structure for Q61727
Antibody Generation
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant protein of IL-10R extracellular domain. The IgG fraction of the culture supernatant was purified by Protein A/G affinity chromatography.
Reconstitution
Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-IL-10 receptor alpha antibody
Western Blot (WB)
1. Western blot: Yes (1:500-1000)

Other Notes

Small volumes of anti-IL-10 receptor alpha antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL-10 receptor alpha purchase

MBS690469 is an antibody targeting IL-10 receptor alpha. Also known as Rat Anti-Mouse IL-10 receptor alpha. Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-10 receptor alpha. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-10 receptor subunit alpha
NCBI Official Synonym Full Names
interleukin 10 receptor, alpha
NCBI Official Symbol
Il10ra
NCBI Official Synonym Symbols
Il10r; CDw210; CDw210a; mIL-10R; AW553859
UniProt Protein Name
Interleukin-10 receptor subunit alpha
UniProt Synonym Protein Names
CDw210a; Interleukin-10 receptor subunit 1
UniProt Gene Name
Il10ra
UniProt Synonym Gene Names
Il10r; IL-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; IL-10R subunit 1; IL-10R1
UniProt Entry Name
I10R1_MOUSE
NCBI Protein Information
interleukin-10 receptor subunit alpha; IL-10R1; IL-10RA; IL-10R subunit 1; IL-10R subunit alpha; IL-10 receptor subunit alpha; interleukin-10 receptor subunit 1

UniProt Comments for IL-10 receptor alpha

Function: Receptor for IL10; binds IL10 with a high affinity.

Subcellular location: Membrane; Single-pass type I membrane protein.

Sequence similarities: Belongs to the type II cytokine receptor family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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