Rat Anti-CXCL15 Monoclonal Antibody – Cat# MBS690473

CXCL15 Antibody – Rat Monoclonal

Name: CXCL15 Antibody; Monoclonal; Rat; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS690473
Price: 875 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS690473

CXCL15/Lungkine, also named WECHE, is a member of the ELR motif-containing CXC chemokines. Lungkine is a CXC chemokine that is expressed in lung epithelial cells and, to a lesser extent, in certain fetal tissues. No human homolog has been identified and a… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CXCL15, Monoclonal Antibody

Full Product Name

Rat Anti-Mouse CXCL15

Product Gene Name

anti-CXCL15 antibody

Product Synonym Names

CXCL15

Clonality

Monoclonal

Isotype

IgG2

Clone Number

(16M7)

Host

Rat

Species Reactivity

Mouse

Form/Format

Lyophilized

Preparation and Storage

Lyophilized samples are stable for 2 years from date of receipt when stored at -70 degree C. Reconstituted antibody can be aliquoted and stored frozen at < -20 degree C for at least for six months without detectable loss of activity.

Molecular Weight

19,091 Da

Chromosome Location

Chromosome: 5; NC_000071.6 (90794534..90803067). Location: 5 E1; 5 44.78 cM

3D Structure

ModBase 3D Structure for Q9WVL7

Antibody Generation

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat) immunized with mouse recombinant protein of CXCL15.

Reconstitution

Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml.

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-CXCL15 antibody

Western Blot (WB)

Other Notes

Small volumes of anti-CXCL15 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CXCL15 purchase

MBS690473 is an antibody targeting CXCL15. Also known as Rat Anti-Mouse CXCL15. Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for CXCL15. It may not necessarily be applicable to this product.

NCBI GI #

6755436

NCBI GeneID

20309

NCBI Accession #

NP_035469.1

UniProt Primary Accession #

Q9WVL7

UniProt Secondary Accession #

Q3UQ15

UniProt Related Accession #

Q9WVL7

GenBank Nucleotide #

NM_011339.2

NCBI Official Full Name

C-X-C motif chemokine 15

NCBI Official Synonym Full Names

chemokine (C-X-C motif) ligand 15

NCBI Official Symbol

Cxcl15

NCBI Official Synonym Symbols

Il8; weche; Scyb15; lungkine

UniProt Protein Name

C-X-C motif chemokine 15

UniProt Synonym Protein Names

Lungkine; Small-inducible cytokine B15

Protein Family

C-X-C motif chemokine

UniProt Gene Name

Cxcl15

UniProt Synonym Gene Names

Scyb15

UniProt Entry Name

CXL15_MOUSE

NCBI Protein Information

C-X-C motif chemokine 15; interleukin 8; small-inducible cytokine B15; small inducible cytokine subfamily B, member 15

UniProt Comments for CXCL15

Function: Chemotactic for neutrophils. Involved in lung-specific neutrophil trafficking during normal and inflammatory conditions. Ref.1 Ref.5

Subcellular location: Secreted Ref.1.

Tissue specificity: Expression restricted to the lung, produced by bronchoepithelial cells and is released into the airways. Expressed at low levels in fetal lung. Ref.1 Ref.5

Induction: By inflammation; in lung. Ref.1

Disruption phenotype: Mice develop normally and are fertile. They display normal leukocyte subpopulations in peripheral blood and bone marrow, but the amount of neutrophils is reduced in the airspace. Susceptibility to pneumonia induced by K.pneumoniae is increased with decreased survival and increased bacterial burden in lung. Ref.5

Sequence similarities: Belongs to the intercrine alpha (chemokine CxC) family.

Research Articles on CXCL15

1. The HIF-1alpha/IL-8 signaling pathway plays a critical role in the protective effects of endothelial progenitor cells in the ischemic hind limb of diabetic mice.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CXCL15 antibody

Products by Pathway	Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram

Diseases associated with anti-CXCL15 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>3 publications with CXCL15 and Inflammation
Lung Diseases Antibodies	>2 publications with CXCL15 and Lung Diseases
Necrosis Antibodies	>1 publications with CXCL15 and Necrosis
Skin Diseases Antibodies	>1 publications with CXCL15 and Skin Diseases
Pneumonia Antibodies	>1 publications with CXCL15 and Pneumonia

Organs/Tissues associated with anti-CXCL15 antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>4 publications with CXCL15 and Lung