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HGF Activator Inhibitor Type 2 (HAI-2) Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS690526

HAIs (HGF activator inhibitor type 2) belong to the Kunitz-type serine protease inhibitor family. HAIs target HGF activator and are involved in the regulation of proteolytic activation of HGF in injured tissues. Human HAI-1 transcript is expressed in various… More details

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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
HGF Activator Inhibitor Type 2 (HAI-2), Monoclonal Antibody
Full Product Name
Rat Anti-Mouse HGF Activator Inhibitor Type 2 (HAI-2)
Product Gene Name
Product Synonym Names
Anti-mouse HGF Activator Inhibitor type 1 [HAI-2] (#7F52)
Clonality
Monoclonal
Isotype
IgG2
Clone Number
(7F52)
Host
Rat
Species Reactivity
Mouse
Form/Format
The IgG fraction of culture supernatant was purified by Protein A/G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS). Lyophilized samples are stable for 2 years from date of receipt when stored at
Purity/Purification
Protein A/G affinity chromatography
Specificity
This antibody detects mouse HAI-2, but not HAI-1 in Western blotting.
Preparation and Storage
Lyophilized samples are stable for 2 years from date of receipt when stored at -70 degree C. Reconstituted antibody can be aliquoted and stored frozen at < -20 degree C for at least for six months without detectable loss of activity.
Molecular Weight
27,914 Da
Chromosome Location
Chromosome: 7; NC_000073.6 (29256325..29281977, complement). Location: 7 B1; 7
3D Structure
ModBase 3D Structure for Q9WU03
Antibody Generation
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant protein of the common extracellular domain of HAI-2 isoforms. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography.
Reconstitution
Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-HAI-2 antibody
Western Blot (WB)
Application Notes for anti-HAI-2 antibody
1. Western blot: Yes (1:500-1000)

Other Notes

Small volumes of anti-HAI-2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HAI-2 purchase

MBS690526 is an antibody targeting HAI-2. Also known as Rat Anti-Mouse HGF Activator Inhibitor Type 2 (HAI-2). Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for HAI-2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
kunitz-type protease inhibitor 2 isoform b
NCBI Official Synonym Full Names
serine protease inhibitor, Kunitz type 2
NCBI Official Symbol
Spint2
NCBI Official Synonym Symbols
HAI-2; C76321; AL024025
UniProt Protein Name
Kunitz-type protease inhibitor 2
UniProt Synonym Protein Names
Hepatocyte growth factor activator inhibitor type 2
UniProt Gene Name
Spint2
UniProt Synonym Gene Names
Hai2; HAI-2
UniProt Entry Name
SPIT2_MOUSE
NCBI Protein Information
kunitz-type protease inhibitor 2; hepatocyte growth factor activator inhibitor type 2

UniProt Comments for HAI-2

Function: Inhibitor of HGF activator.

Subcellular location: Membrane; Single-pass type I membrane protein

Potential.

Tissue specificity: Isoform 2 is more predominantly expressed than isoform 1.

Domain: This inhibitor contains two inhibitory domains.

Sequence similarities: Contains 2 BPTI/Kunitz inhibitor domains.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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