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Layilin (LAYN) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS690573

Layilin (named after the L-A-Y-I-L-I six amino acid motif in the molecules transmembrane segment) is a member of the animal C-type lectin family. Layilin binds specifically to hyaluronan and is found in the extracellular matrix of most animal tissues and in… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Layilin (LAYN), Monoclonal Antibody
Full Product Name
Mouse Anti-Human Layilin
Product Gene Name
Product Synonym Names
LAYN
Clonality
Monoclonal
Isotype
IgG2
Clone Number
(4F33)
Host
Mouse
Species Reactivity
Human
Form/Format
Lyophilized
Preparation and Storage
Lyophilized samples are stable for 2 years from date of receipt when stored at -70 degree C. Reconstituted antibody can be aliquoted and stored frozen at < -20 degree C for at least for six months without detectable loss of activity.
Molecular Weight
43,108 Da
Chromosome Location
Chromosome: 11; NC_000011.10 (111540508..111561745). Location: 11q23.1
3D Structure
ModBase 3D Structure for Q6UX15
Antibody Generation
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Layilin.
Reconstitution
Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-LAYN antibody
Western Blot (WB)

Other Notes

Small volumes of anti-LAYN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LAYN purchase

MBS690573 is an antibody targeting LAYN. Also known as Mouse Anti-Human Layilin. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for LAYN. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
layilin isoform 1
NCBI Official Synonym Full Names
layilin
NCBI Official Symbol
LAYN
UniProt Protein Name
Layilin
Protein Family
UniProt Gene Name
LAYN
UniProt Entry Name
LAYN_HUMAN
NCBI Protein Information
layilin

UniProt Comments for LAYN

Function: Receptor for hyaluronate. Ref.6

Subunit structure: Interacts with NF2, RDX and TLN1

By similarity.

Subcellular location: Membrane; Single-pass type I membrane protein

Potential. Note: Colocalizes with TLN1 at the membrane ruffles

By similarity.

Domain: The C-terminal domain interacts with the N-terminal domain of RDX

By similarity.

Sequence similarities: Contains 1 C-type lectin domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-LAYN antibody

Organs/Tissues associated with anti-LAYN antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >1 publications with LAYN and Lung
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