Rat Anti-LGALS1 Monoclonal Antibody – Cat# MBS690679

Galectin-1 (LGALS1) Antibody – Rat Monoclonal

Name: LGALS1 Antibody; Monoclonal; Rat; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS690679
Price: 875 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS690679

The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Galectin-1 (Lgals1), Monoclonal Antibody

Full Product Name

Rat Anti-Mouse Galectin-1

Product Gene Name

anti-Lgals1 antibody

Product Synonym Names

Anti-mouse Galectin-1 (#9J26)

Clonality

Monoclonal

Isotype

IgG2

Clone Number

(9J26)

Host

Rat

Species Reactivity

Mouse

Form/Format

The IgG fraction of culture supernatant was purified by Protein A/G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS). Lyophilized samples are stable for 2 years from date of receipt when stored at

Purity/Purification

Protein A/G affinity chromatography

Specificity

This antibody detects mouse Galectin-1 in Western blotting.

Preparation and Storage

Lyophilized samples are stable for 2 years from date of receipt when stored at -70 degree C. Reconstituted antibody can be aliquoted and stored frozen at < -20 degree C for at least for six months without detectable loss of activity.

Molecular Weight

14,866 Da

Chromosome Location

Chromosome: 15; NC_000081.6 (78926725..78930465). Location: 15 E; 15 37.7 cM

3D Structure

ModBase 3D Structure for P16045

Antibody Generation

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant Galectin-1. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography.

Reconstitution

Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml.

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-Lgals1 antibody

Western Blot (WB), Immunohistochemistry (IHC) - Formalin

Application Notes for anti-Lgals1 antibody

1. Western blot: Yes (1:500-1000) 2. IHC (frozen): Yes (1:50-200)

Other Notes

Small volumes of anti-Lgals1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Lgals1 purchase

MBS690679 is an antibody targeting Lgals1. Also known as Rat Anti-Mouse Galectin-1. Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for Lgals1. It may not necessarily be applicable to this product.

NCBI GI #

6678682

NCBI GeneID

16852

NCBI Accession #

NP_032521.1

UniProt Primary Accession #

P16045

UniProt Secondary Accession #

P05163; P11946; P17601; Q4FZH4; Q99M27; Q9D0X0

UniProt Related Accession #

P16045

GenBank Nucleotide #

NM_008495.2

NCBI Official Full Name

galectin-1

NCBI Official Synonym Full Names

lectin, galactose binding, soluble 1

NCBI Official Symbol

Lgals1

NCBI Official Synonym Symbols

L14; Gal-1; Galbp; L-14.5; Lect14; AA410090; galectin-1

UniProt Protein Name

Galectin-1

UniProt Synonym Protein Names

14 kDa lectin; Beta-galactoside-binding lectin L-14-I; Galaptin; Lactose-binding lectin 1; Lectin galactoside-binding soluble 1; S-Lac lectin 1

Protein Family

Galectin

UniProt Gene Name

Lgals1

UniProt Synonym Gene Names

Gbp; Gal-1

UniProt Entry Name

LEG1_MOUSE

NCBI Protein Information

galectin-1; galaptin; 14 kDa lectin; S-Lac lectin 1; lactose-binding lectin 1; beta-galactoside binding protein; lectin galactoside-binding soluble 1; beta-galactoside-binding lectin L-14-I

UniProt Comments for Lgals1

Function: May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Strong inducer of T-cell apoptosis

By similarity.

Subunit structure: Homodimer. Binds LGALS3BP. Interacts with CD2, CD3, CD4, CD7, CD43 and CD45. Interacts with laminin

By similarity.

Subcellular location: Secreted › extracellular space › extracellular matrix

By similarity.

Sequence similarities: Contains 1 galectin domain.

Caution: Was originally (Ref.9) thought to originate from human.

Sequence caution: The sequence AAA37313.1 differs from that shown. Reason: Frameshift at several positions. The sequence AK004298 differs from that shown. Reason: Frameshift at position 117.

Research Articles on Lgals1

1. results strengthen the notion that Gal-1 is required for healthy gestation and highlight Gal-1 as a valuable biomarker for early PE diagnosis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Lgals1 antibody

Products by Pathway	Pathway Diagram
PodNet: Protein-protein Interactions In The Podocyte Pathway antibodies	PodNet: Protein-protein Interactions In The Podocyte Pathway Diagram
XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway antibodies	XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway Diagram

Diseases associated with anti-Lgals1 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>351 publications with Lgals1 and Neoplasms
Inflammation Antibodies	>110 publications with Lgals1 and Inflammation
Disease Models, Animal Antibodies	>65 publications with Lgals1 and Disease Models, Animal
Neoplasm Metastasis Antibodies	>64 publications with Lgals1 and Neoplasm Metastasis
Adenocarcinoma Antibodies	>57 publications with Lgals1 and Adenocarcinoma
Neoplasms, Experimental Antibodies	>46 publications with Lgals1 and Neoplasms, Experimental
Breast Neoplasms Antibodies	>37 publications with Lgals1 and Breast Neoplasms
Lung Diseases Antibodies	>29 publications with Lgals1 and Lung Diseases
Lung Neoplasms Antibodies	>29 publications with Lgals1 and Lung Neoplasms
Necrosis Antibodies	>27 publications with Lgals1 and Necrosis

Organs/Tissues associated with anti-Lgals1 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>336 publications with Lgals1 and Blood
Brain Antibodies	>85 publications with Lgals1 and Brain
Muscle Antibodies	>59 publications with Lgals1 and Muscle
Lung Antibodies	>48 publications with Lgals1 and Lung
Embryonic Tissue Antibodies	>45 publications with Lgals1 and Embryonic Tissue
Liver Antibodies	>44 publications with Lgals1 and Liver
Kidney Antibodies	>40 publications with Lgals1 and Kidney
Bone Marrow Antibodies	>34 publications with Lgals1 and Bone Marrow
Spleen Antibodies	>31 publications with Lgals1 and Spleen
Intestine Antibodies	>26 publications with Lgals1 and Intestine