Mouse Anti-CCL-27 Monoclonal Antibody – Cat# MBS690682

CCL-27 Antibody – Mouse Monoclonal

Name: CCL-27 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS690682
Price: 875 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS690682

CTACK or CCL-27 is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor. Both CTACK and CCR10 are expressed in normal and irritated epithelial cells. CTACK selectively attracts CLA+ T-cells and directs them into the skin. CTACK… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

CCL-27, Monoclonal Antibody

Full Product Name

Mouse Anti-Human CCL-27

Product Gene Name

anti-CCL-27 antibody

Product Synonym Names

CCL27; ALP; ILC; CTAK; CTACK; PESKY; ESKINE; SCYA27

Clonality

Monoclonal

Isotype

IgG1

Clone Number

(7H44)

Host

Mouse

Species Reactivity

Human

Form/Format

Lyophilized

Preparation and Storage

Lyophilized samples are stable for 2 years from date of receipt when stored at -70 degree C. Reconstituted antibody can be aliquoted and stored frozen at < -20 degree C for at least for six months without detectable loss of activity.

Molecular Weight

12,618 Da

Chromosome Location

Chromosome: 9; NC_000009.12 (34661896..34662692, complement). Location: 9p13

OMIM

604833

3D Structure

ModBase 3D Structure for Q9Y4X3

Antibody Generation

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of CCL-27 (also called Cutaneous T-cell-attracting chemokine (CTACK)).

Reconstitution

Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml.

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-CCL-27 antibody

Western Blot (WB), Immunohistochemistry (IHC), Neutr

Other Notes

Small volumes of anti-CCL-27 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCL-27 purchase

MBS690682 is an antibody targeting CCL-27. Also known as Mouse Anti-Human CCL-27. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CCL-27. It may not necessarily be applicable to this product.

NCBI GI #

5730035

NCBI GeneID

10850

NCBI Accession #

NP_006655.1

UniProt Primary Accession #

Q9Y4X3

UniProt Related Accession #

Q9Y4X3

GenBank Nucleotide #

NM_006664.2

NCBI Official Full Name

C-C motif chemokine 27

NCBI Official Synonym Full Names

chemokine (C-C motif) ligand 27

NCBI Official Symbol

CCL27

NCBI Official Synonym Symbols

ALP; ILC; CTAK; CTACK; PESKY; ESKINE; SCYA27

UniProt Protein Name

C-C motif chemokine 27

UniProt Synonym Protein Names

CC chemokine ILC; Cutaneous T-cell-attracting chemokine; CTACK; ESkine; IL-11 R-alpha-locus chemokine; Skinkine; Small-inducible cytokine A27

UniProt Gene Name

CCL27

UniProt Synonym Gene Names

ILC; SCYA27; CTACK

UniProt Entry Name

CCL27_HUMAN

NCBI Protein Information

C-C motif chemokine 27; skinkine; CC chemokine ILC; IL-11 Ralpha-locus chemokine; small-inducible cytokine A27; IL-11 R-alpha-locus chemokine; cutaneous T-cell attracting chemokine; cutaneous T-cell-attracting chemokine; small inducible cytokine subfamily A (Cys-Cys), member 27

NCBI Summary for CCL-27

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Jul 2008]

UniProt Comments for CCL-27

Function: Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. Binds to CCR10.

Subunit structure: Monomer, dimer, and tetramer. Heparin avidly promotes oligomerization. Ref.5

Subcellular location: Secreted.

Tissue specificity: Testis, thymus, placenta, ovary and skin.

Sequence similarities: Belongs to the intercrine beta (chemokine CC) family.

Research Articles on CCL-27

1. CCL27 chemokine implicates cholesteatoma keratinocytes as contributors in cholesteatoma progression.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CCL-27 antibody

Reference Product	PubMed Publications
CCR10 antibody	>56 publications with CCL-27 and CCR10
CXCL10 antibody	>19 publications with CCL-27 and CXCL10
CCL20 antibody	>19 publications with CCL-27 and CCL20
CCR7 antibody	>14 publications with CCL-27 and CCR7
CCL21 antibody	>12 publications with CCL-27 and CCL21
CCR5 antibody	>5 publications with CCL-27 and CCR5
CCR6 antibody	>4 publications with CCL-27 and CCR6
CCBP2 antibody	>4 publications with CCL-27 and CCBP2
CCL25 antibody	>3 publications with CCL-27 and CCL25
CXCR5 antibody	>1 publications with CCL-27 and CXCR5

Pathways associated with anti-CCL-27 antibody

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram

Diseases associated with anti-CCL-27 antibody

Disease Name	Pubmed Publications
Immune System Diseases Antibodies	>55 publications with CCL-27 and Immune System Diseases
Inflammation Antibodies	>43 publications with CCL-27 and Inflammation
Necrosis Antibodies	>32 publications with CCL-27 and Necrosis
Disease Models, Animal Antibodies	>11 publications with CCL-27 and Disease Models, Animal
Dermatitis, Allergic Contact Antibodies	>11 publications with CCL-27 and Dermatitis, Allergic Contact
Drug-Related Side Effects and Adverse Reactions Antibodies	>6 publications with CCL-27 and Drug-Related Side Effects and Adverse Reactions
Nervous System Diseases Antibodies	>5 publications with CCL-27 and Nervous System Diseases
Liver Diseases Antibodies	>3 publications with CCL-27 and Liver Diseases
Liver Neoplasms Antibodies	>2 publications with CCL-27 and Liver Neoplasms
Precancerous Conditions Antibodies	>2 publications with CCL-27 and Precancerous Conditions

Organs/Tissues associated with anti-CCL-27 antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>5 publications with CCL-27 and Lung
Connective Tissue Antibodies	>4 publications with CCL-27 and Connective Tissue
Eye Antibodies	>2 publications with CCL-27 and Eye
Testis Antibodies	>2 publications with CCL-27 and Testis
Placenta Antibodies	>2 publications with CCL-27 and Placenta