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Endocan/ESM-1 (ESM-1) Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS690697

Endocan (endothelial cell proteoglycan), also known as endothelialcell specific molecule1 (ESM-1), is a 50 kDa monomeric, secreted, cysteinerich proteoglycan identified initially in endothelial cells of the kidney and lung. Mouse Endocan is synthesized as a… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Endocan/ESM-1, Monoclonal Antibody
Full Product Name
Rat Anti-Mouse Endocan/ESM-1
Product Gene Name
anti-ESM-1 antibody
Product Synonym Names
Anti-mouse Endocan (#5F44)
Clonality
Monoclonal
Isotype
IgG2
Clone Number
(5J44)
Host
Rat
Species Reactivity
Mouse
Form/Format
The IgG fraction of culture supernatant was purified by Protein A/G affinity chromatography and lyophilized from a 0.2 um filtered solution in phosphate-buffered saline (PBS). Lyophilized samples are stable for 2 years from date of receipt when stored at
Purity/Purification
Protein A/G affinity chromatography
Specificity
This antibody detects mouse Endocan in Western blotting.
Preparation and Storage
Lyophilized samples are stable for 2 years from date of receipt when stored at -70 degree C. Reconstituted antibody can be aliquoted and stored frozen at < -20 degree C for at least for six months without detectable loss of activity.
Molecular Weight
20,043 Da
Chromosome Location
Chromosome: 13; NC_000079.6 (113209659..113218104). Location: 13 D2.2; 13
3D Structure
ModBase 3D Structure for Q9QYY7
Antibody Generation
This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with purified mouse recombinant Endocan. The IgG2 fraction of the culture supernatant was purified by Protein A/G affinity chromatography.
Reconstitution
Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-ESM-1 antibody
Western Blot (WB)
Application Notes for anti-ESM-1 antibody
1. Western blot: Yes (1:500-1000)

Other Notes

Small volumes of anti-ESM-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ESM-1 purchase

MBS690697 is an antibody targeting ESM-1. Also known as Rat Anti-Mouse Endocan/ESM-1. Reactive in Mouse. Host: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for ESM-1. It may not necessarily be applicable to this product.

NCBI GI #
14196342
NCBI GeneID
71690
NCBI Accession #
NP_076101.1
UniProt Primary Accession #
Q9QYY7
UniProt Related Accession #
Q9QYY7
GenBank Nucleotide #
NM_023612.3
NCBI Official Full Name
endothelial cell-specific molecule 1
NCBI Official Synonym Full Names
endothelial cell-specific molecule 1
NCBI Official Symbol
Esm1
NCBI Official Synonym Symbols
ESM-1; AV004503; 0610042H23Rik
UniProt Protein Name
Endothelial cell-specific molecule 1
UniProt Gene Name
Esm1
UniProt Synonym Gene Names
ESM-1
UniProt Entry Name
ESM1_MOUSE
NCBI Protein Information
endothelial cell-specific molecule 1

UniProt Comments for ESM-1

Function: Involved in angiogenesis; promotes angiogenic sprouting. May have potent implications in lung endothelial cell-leukocyte interactions

By similarity.

Subcellular location: Secreted

By similarity.

Post-translational modification: O-glycosylated; contains chondroitin sulfate and dermatan sulfate

By similarity.

Sequence similarities: Contains 1 IGFBP N-terminal domain.
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Research Articles on ESM-1

1. endocan is normally present in the mouse brain and prior vascular perfusion with FITC may provide a useful tool for identify newly forming blood vessels.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-ESM-1 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >38 publications with ESM-1 and Neoplasms
 Carcinoma Antibodies  >18 publications with ESM-1 and Carcinoma
 Inflammation Antibodies  >12 publications with ESM-1 and Inflammation
 Neoplasm Metastasis Antibodies  >10 publications with ESM-1 and Neoplasm Metastasis
 Lung Diseases Antibodies  >10 publications with ESM-1 and Lung Diseases
 Lung Neoplasms Antibodies  >9 publications with ESM-1 and Lung Neoplasms
 Liver Neoplasms Antibodies  >6 publications with ESM-1 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >5 publications with ESM-1 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >5 publications with ESM-1 and Liver Diseases
 Cell Transformation, Neoplastic Antibodies  >4 publications with ESM-1 and Cell Transformation, Neoplastic

Organs/Tissues associated with anti-ESM-1 antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >16 publications with ESM-1 and Lung
 Kidney Antibodies  >12 publications with ESM-1 and Kidney
 Liver Antibodies  >8 publications with ESM-1 and Liver
 Brain Antibodies  >7 publications with ESM-1 and Brain
 Adrenal Gland Antibodies  >2 publications with ESM-1 and Adrenal Gland
 Spleen Antibodies  >1 publications with ESM-1 and Spleen
 Mammary Gland Antibodies  >1 publications with ESM-1 and Mammary Gland
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