Mouse Anti-LGALS4 Monoclonal Antibody – Cat# MBS690870

Galectin-4 (LGALS4) Antibody – Mouse Monoclonal

Name: LGALS4 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS690870
Price: 875 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS690870

Galectin-4 is a member of the subfamily of galectins composed of two carbohydrate recognition domains having similar peptide chains. The galectins are a family of beta-galactoside-binding proteins having a role in modulating cell-cell and cell-matrix… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Galectin-4 (LGALS4), Monoclonal Antibody

Full Product Name

Mouse Anti-Human Galectin-4

Product Gene Name

anti-LGALS4 antibody

Product Synonym Names

LGALS3; L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS2

Clonality

Monoclonal

Isotype

IgG2

Clone Number

(1D12)

Host

Mouse

Species Reactivity

Human

Form/Format

Lyophilized from a 0.2um filtered solution in phosphate-buffered saline (PBS).

Purity/Purification

Protein G affinity chromatography

Preparation and Storage

Lyophilized samples are stable for 2 years from date of receipt when stored at -70 degree C. Reconstituted antibody can be aliquoted and stored frozen at < -20 degree C for at least for six months without detectable loss of activity.Avoid repeated freeze-thaw cycles

Molecular Weight

35,941 Da

Chromosome Location

Chromosome: 19; NC_000019.10 (38801671..38813100, complement). Location: 19q13.2

OMIM

602518

3D Structure

ModBase 3D Structure for P56470

Antibody Generation

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of Galectin-4.

Antigen

Recombinant human Galectin-4

Reconstitution

Reconstitute the antibody with 200 ul sterile PBS and the final concentration is 500 ug/ml. Reconstituted antibody can also be aliquoted and stored frozen at <-20 degree C for at least six months without detectable loss of activity.

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-LGALS4 antibody

Western Blot (WB)

Application Notes for anti-LGALS4 antibody

Western Blot: Yes (1:500-1000)
Optimal dilutions should be determined by each laboratory for each application.

Other Notes

Small volumes of anti-LGALS4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LGALS4 purchase

MBS690870 is an antibody targeting LGALS4. Also known as Mouse Anti-Human Galectin-4. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for LGALS4. It may not necessarily be applicable to this product.

NCBI GI #

5453712

NCBI GeneID

3960

NCBI Accession #

NP_006140.1

UniProt Primary Accession #

P56470

UniProt Related Accession #

P56470

GenBank Nucleotide #

NM_006149.3

NCBI Official Full Name

galectin-4

NCBI Official Synonym Full Names

lectin, galactoside-binding, soluble, 4

NCBI Official Symbol

LGALS4

NCBI Official Synonym Symbols

GAL4; L36LBP

UniProt Protein Name

Galectin-4

UniProt Synonym Protein Names

Antigen NY-CO-27; L-36 lactose-binding protein; L36LBP; Lactose-binding lectin 4

Protein Family

Galectin

UniProt Gene Name

LGALS4

UniProt Synonym Gene Names

Gal-4; L36LBP

UniProt Entry Name

LEG4_HUMAN

NCBI Protein Information

galectin-4; gal-4; galectin 4; antigen NY-CO-27; lactose-binding lectin 4; L-36 lactose-binding protein

NCBI Summary for LGALS4

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The expression of this gene is restricted to small intestine, colon, and rectum, and it is underexpressed in colorectal cancer. [provided by RefSeq, Jul 2008]

UniProt Comments for LGALS4

Function: Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions.

Subunit structure: Monomer

By similarity.

Domain: Contains two homologous but distinct carbohydrate-binding domains.

Sequence similarities: Contains 2 galectin domains.

Research Articles on LGALS4

1. Data indicate that galectin-4 elicits tumor promotion in vitro and in vivo through activation of IL-6/NF-kappaB/STAT3 signaling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LGALS4 antibody

Reference Product	PubMed Publications
CCNB1 antibody	>1 publications with LGALS4 and CCNB1

Diseases associated with anti-LGALS4 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>43 publications with LGALS4 and Neoplasms
Carcinoma Antibodies	>26 publications with LGALS4 and Carcinoma
Colorectal Neoplasms Antibodies	>19 publications with LGALS4 and Colorectal Neoplasms
Adenocarcinoma Antibodies	>17 publications with LGALS4 and Adenocarcinoma
Inflammation Antibodies	>12 publications with LGALS4 and Inflammation
Neoplasm Metastasis Antibodies	>7 publications with LGALS4 and Neoplasm Metastasis
Liver Diseases Antibodies	>4 publications with LGALS4 and Liver Diseases
Liver Neoplasms Antibodies	>4 publications with LGALS4 and Liver Neoplasms
Brain Diseases Antibodies	>4 publications with LGALS4 and Brain Diseases
Breast Neoplasms Antibodies	>4 publications with LGALS4 and Breast Neoplasms

Organs/Tissues associated with anti-LGALS4 antibody

Organ/Tissue Name	Pubmed Publications
Intestine Antibodies	>40 publications with LGALS4 and Intestine
Blood Antibodies	>27 publications with LGALS4 and Blood
Liver Antibodies	>18 publications with LGALS4 and Liver
Stomach Antibodies	>16 publications with LGALS4 and Stomach
Lung Antibodies	>10 publications with LGALS4 and Lung
Kidney Antibodies	>9 publications with LGALS4 and Kidney
Brain Antibodies	>9 publications with LGALS4 and Brain
Embryonic Tissue Antibodies	>6 publications with LGALS4 and Embryonic Tissue
Bladder Antibodies	>4 publications with LGALS4 and Bladder
Pancreas Antibodies	>3 publications with LGALS4 and Pancreas