Rabbit Anti-IL-17B Polyclonal Antibody – Cat# MBS691066

IL-17B Antibody – Rabbit Polyclonal

Name: IL-17B Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS691066
Price: 605 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS691066

The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

IL-17B, Polyclonal Antibody

Full Product Name

Rabbit Anti-Human IL-17B

Product Gene Name

anti-IL-17B antibody

Product Synonym Names

Antigen-Affinity Purified Polyclonal Antibodies Anti-human IL-17B

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Form/Format

Lyophilized

Purity/Purification

Affinity chromatography

Molecular Weight

20,437 Da

Chromosome Location

Chromosome: 5; NC_000005.10 (149374267..149404202, complement). Location: 5q33.1

OMIM

604627

3D Structure

ModBase 3D Structure for Q9UHF5

Antibody Generation

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hIL-17B (human Interleukin-17B) Anti-hIL-17B specific antibody was purified by affinity chromatography employing immobilized hIL-17B matrix.

Buffer

0.5 x PBS; pH 7.4

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-IL-17B antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-IL-17B antibody

Western Blot: To detect hIL-17B by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hIL-17B is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

Other Notes

Small volumes of anti-IL-17B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL-17B purchase

MBS691066 is an antibody targeting IL-17B. Also known as Rabbit Anti-Human IL-17B. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-17B. It may not necessarily be applicable to this product.

NCBI GI #

7657228

NCBI GeneID

27190

NCBI Accession #

NP_055258.1

UniProt Primary Accession #

Q9UHF5

UniProt Secondary Accession #

Q14CE5

UniProt Related Accession #

Q9UHF5

GenBank Nucleotide #

NM_014443.2

NCBI Official Full Name

interleukin-17B

NCBI Official Synonym Full Names

interleukin 17B

NCBI Official Symbol

IL17B

NCBI Official Synonym Symbols

NIRF; IL-20; IL-17B; ZCYTO7

UniProt Protein Name

Interleukin-17B

UniProt Synonym Protein Names

Cytokine Zcyto7; Interleukin-20; IL-20; Neuronal interleukin-17-related factor

Protein Family

Interleukin

UniProt Gene Name

IL17B

UniProt Synonym Gene Names

IL20; NIRF; ZCYTO7; IL-17B; IL-20

UniProt Entry Name

IL17B_HUMAN

NCBI Protein Information

interleukin-17B; interleukin 20; interleukin-20; cytokine Zcyto7; interleukin-17 beta; cytokine-like protein ZCYTO7; neuronal interleukin-17 related factor; neuronal interleukin-17-related factor

NCBI Summary for IL-17B

The protein encoded by this gene is a T cell-derived cytokine that shares sequence similarity with IL17. This cytokine was reported to stimulate the release of TNF alpha (TNF) and IL1 beta (IL1B) from a monocytic cell line. Immunohistochemical analysis of several nerve tissues indicated that this cytokine is primarily localized to neuronal cell bodies. [provided by RefSeq, Jul 2008]

UniProt Comments for IL-17B

Function: Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.

Subcellular location: Secreted.

Tissue specificity: Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.

Sequence similarities: Belongs to the IL-17 family.

Research Articles on IL-17B

1. IL-17B can enhance the effects of TNF-alpha on the production of cytokines and chemokines that control immune cell trafficking and neutrophil homeostasis in the inflamed tissues.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-IL-17B antibody

Products by Pathway	Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
IL17 Signaling Pathway antibodies	IL17 Signaling Pathway Diagram

Diseases associated with anti-IL-17B antibody

Disease Name	Pubmed Publications
Necrosis Antibodies	>5 publications with IL-17B and Necrosis
Inflammation Antibodies	>4 publications with IL-17B and Inflammation
Disease Models, Animal Antibodies	>3 publications with IL-17B and Disease Models, Animal
Neoplasms Antibodies	>3 publications with IL-17B and Neoplasms
Drug-Related Side Effects and Adverse Reactions Antibodies	>1 publications with IL-17B and Drug-Related Side Effects and Adverse Reactions
Liver Neoplasms Antibodies	>1 publications with IL-17B and Liver Neoplasms

Organs/Tissues associated with anti-IL-17B antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>4 publications with IL-17B and Bone
Heart Antibodies	>1 publications with IL-17B and Heart
Lung Antibodies	>1 publications with IL-17B and Lung