Rabbit Anti-IL-17E Polyclonal Antibody – Cat# MBS691154

IL-17E Antibody – Rabbit Polyclonal

Name: IL-17E Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS691154
Price: 605 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS691154

The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

IL-17E, Polyclonal Antibody

Full Product Name

Rabbit Anti-Human IL-17E

Product Gene Name

anti-IL-17E antibody

Product Synonym Names

Antigen-Affinity Purified Polyclonal Antibodies Anti-human IL-17E

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Form/Format

Lyophilized

Purity/Purification

Affinity chromatography

Molecular Weight

20,330 Da

Chromosome Location

Chromosome: 14; NC_000014.9 (23372809..23376403). Location: 14q11.2

OMIM

605658

3D Structure

ModBase 3D Structure for Q9H293

Antibody Generation

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hIL-17E (human IL-17E). Anti-hIL-17E specific antibody was purified by affinity chromatography employing immobilized hIL-17E matrix.

Buffer

0.5 x PBS; pH 7.4

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Applications Tested/Suitable for anti-IL-17E antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-IL-17E antibody

Western Blot: To detect hIL-17E by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hIL-17E is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

Other Notes

Small volumes of anti-IL-17E antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL-17E purchase

MBS691154 is an antibody targeting IL-17E. Also known as Rabbit Anti-Human IL-17E. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-17E. It may not necessarily be applicable to this product.

NCBI GI #

12232485

NCBI GeneID

64806

NCBI Accession #

NP_073626.1

UniProt Primary Accession #

Q9H293

UniProt Secondary Accession #

Q2M3F0; Q8IZV3; Q8WXB0

UniProt Related Accession #

Q9H293

GenBank Nucleotide #

NM_022789.3

NCBI Official Full Name

interleukin-25 isoform 1

NCBI Official Synonym Full Names

interleukin 25

NCBI Official Symbol

IL25

NCBI Official Synonym Symbols

IL17E

UniProt Protein Name

Interleukin-25

UniProt Synonym Protein Names

Interleukin-17E

Protein Family

Interleukin

UniProt Gene Name

IL25

UniProt Synonym Gene Names

IL17E; IL-25; IL-17E

UniProt Entry Name

IL25_HUMAN

NCBI Protein Information

interleukin-25; interleukin-17E

NCBI Summary for IL-17E

The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

UniProt Comments for IL-17E

Function: Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses.

Subcellular location: Secreted.

Tissue specificity: Expressed at low levels in several tissues, including brain, kidney, lung, prostate, testis, spinal cord, adrenal gland, and trachea.

Sequence similarities: Belongs to the IL-17 family.

Research Articles on IL-17E

1. IL-25 expression is markedly reduced during human and experimental fulminant hepatitis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IL-17E antibody

Reference Product	PubMed Publications
IL33 antibody	>11 publications with IL-17E and IL33
ITGAX antibody	>2 publications with IL-17E and ITGAX
IL17RB antibody	>2 publications with IL-17E and IL17RB
IL23A antibody	>1 publications with IL-17E and IL23A

Pathways associated with anti-IL-17E antibody

Products by Pathway	Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
IL17 Signaling Pathway antibodies	IL17 Signaling Pathway Diagram

Diseases associated with anti-IL-17E antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>28 publications with IL-17E and Inflammation
Hypersensitivity Antibodies	>24 publications with IL-17E and Hypersensitivity
Lung Diseases Antibodies	>12 publications with IL-17E and Lung Diseases
Skin Diseases Antibodies	>8 publications with IL-17E and Skin Diseases
Hyperplasia Antibodies	>7 publications with IL-17E and Hyperplasia
Disease Models, Animal Antibodies	>5 publications with IL-17E and Disease Models, Animal
Colitis Antibodies	>4 publications with IL-17E and Colitis
Necrosis Antibodies	>4 publications with IL-17E and Necrosis
Pneumonia Antibodies	>2 publications with IL-17E and Pneumonia
Leukocytosis Antibodies	>1 publications with IL-17E and Leukocytosis