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Endomucin (EMCN) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS691272

Endomucin (endothelial sialomucin; also Endomucin-1/2 and Mucin-14) is an 80 - 120 kDa glycoprotein member of the Endomucin family of proteins. It is expressed on endothelial cells and depending upon its glycosylation pattern, can serve as either a pro- or… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
Endomucin (Emcn), Polyclonal Antibody
Full Product Name
Rabbit Anti-Mouse Endomucin
Product Gene Name
Product Synonym Names
Anti-mouse Endomucin; Endomucin-1/2; Mucin-14; Muc-14
Clonality
Polyclonal
Clone Number
Rabbit IgG
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Lyophilized
Purity/Purification
Protein A purified
Preparation and Storage
The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 degree C. Frozen aliquots are stable for at least 6 months when stored at -20 degree C.
Molecular Weight
27,756 Da
Chromosome Location
Chromosome: 3; NC_000069.6 (137341062..137431069). Location: 3 G3; 3
3D Structure
ModBase 3D Structure for Q9R0H2
Immunogen
Recombinant mouse soluble Endomucin (RT #S01-M64)
Preparation
Produced from sera of rabbits pre-immunized with highly pure (>95%) recombinant mouse soluble Endomucin (Glu20-Ser190) derived from E. coli.
Buffer
PBS
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-Emcn antibody
Western Blot (WB)
Application Notes for anti-Emcn antibody
Western Blot: Use 1-5 ug/ml IF/IHC: Use 5ug/ml

Testing Data of anti-Emcn antibody

Rabbit Anti-EMCN Polyclonal Antibody – Cat# MBS691272

Product References and Citations for anti-Emcn antibody

1.Kinoshita M et al, FEBS Lett 499 (1-2): 121, 2001 2.Kuhn A et al, J Invest Dermatol 119:1388, 2002 3. Matsubara A et al, J Exp Medicine 202:1483, 2005 4. Brachtendorf G et al, Dev Dyn 222:410, 2001 5. Morgan SM et al, Blood 93:165, 1999 6. Samulowitz U et al, Am J Path 160:1669, 2002

Other Notes

Small volumes of anti-Emcn antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Emcn purchase

MBS691272 is an antibody targeting Emcn. Also known as Rabbit Anti-Mouse Endomucin. Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Emcn. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
endomucin isoform 1
NCBI Official Synonym Full Names
endomucin
NCBI Official Symbol
Emcn
NCBI Official Synonym Symbols
Muc14; AI315669; 0610012K22Rik
UniProt Protein Name
Endomucin
UniProt Synonym Protein Names
Endomucin-1/2; Mucin-14
Protein Family
UniProt Gene Name
Emcn
UniProt Synonym Gene Names
Muc14; MUC-14
UniProt Entry Name
MUCEN_MOUSE
NCBI Protein Information
endomucin; MUC-14; mucin-14; endomucin-1; endomucin-1/2; mucin 14, endothelial

UniProt Comments for Emcn

Function: Endothelial sialomucin, also called endomucin or mucin-like sialoglycoprotein, which interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix

By similarity.

Subcellular location: Membrane; Single-pass type I membrane protein

Potential.

Tissue specificity: Highly expressed in heart and kidney, followed by brain, spleen, thymus, liver and lung. Exclusively expressed in endothelial cells. Ref.2

Post-translational modification: Highly O-glycosylated. Sialic acid-rich glycoprotein. Ref.1 Ref.2
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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