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GRO-beta/MIP-2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS691386

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO-beta/MIP-2 is a 7.9 kDa protein consisting of 73 amino acids including… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GRO-beta/MIP-2, Polyclonal Antibody
Full Product Name
Rabbit Anti-Rat GRO-beta/MIP-2
Product Synonym Names
Antigen-Affinity Purified Polyclonal Antibodies Anti-rat GRObeta/MIP-2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Rat
Form/Format
Lyophilized
Purity/Purification
Affinity chromatography
Molecular Weight
10,783 Da
Chromosome Location
Chromosome: 14; NC_005113.3 (18640312..18642357, complement). Location: 14p22
3D Structure
ModBase 3D Structure for P30348
Buffer
PBS; pH 7.2
Neutralization
To yield one-half maximal inhibition [ND50] of the biological activity of Rat GRO/MIP-2 (100 ng/ml), a concentration of 3.0 - 5.0 ug/ml of this antibody is required.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-GRO-beta/MIP-2 antibody
ELISA (EIA), Western Blot (WB), Neutr
Application Notes for anti-GRO-beta/MIP-2 antibody
Western Blot: To detect Rat GRObeta/MIP-2 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant Rat GRObeta/MIP-2 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

Other Notes

Small volumes of anti-GRO-beta/MIP-2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GRO-beta/MIP-2 purchase

MBS691386 is an antibody targeting GRO-beta/MIP-2. Also known as Rabbit Anti-Rat GRO-beta/MIP-2. Reactive in Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for GRO-beta/MIP-2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
C-X-C motif chemokine 2
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 2
NCBI Official Symbol
Cxcl2
NCBI Official Synonym Symbols
Mip-2; Scyb2
UniProt Protein Name
C-X-C motif chemokine 2
UniProt Synonym Protein Names
Cytokine-induced neutrophil chemoattractant 3; CINC-3; Macrophage inflammatory protein 2
UniProt Gene Name
Cxcl2
UniProt Synonym Gene Names
Cinc3; Mip-2; Mip2; Scyb2; CINC-3; MIP2
UniProt Entry Name
CXCL2_RAT
NCBI Protein Information
C-X-C motif chemokine 2; MIP2; CINC-3; macrophage inflammatory protein 2; small inducible cytokine subfamily, member 2; cytokine-induced neutrophil chemoattractant 3

NCBI Summary for GRO-beta/MIP-2

chemokine involved in the pulmonary inflammatory response [RGD, Feb 2006]

UniProt Comments for GRO-beta/MIP-2

Function: Chemotactic for human polymorphonuclear leukocytes but does not induce chemokinesis or an oxidative burst. Contributes to neutrophil activation during inflammation.

Subunit structure: Homotetramer.

Subcellular location: Secreted.

Tissue specificity: At least expressed in the lung and trachea.

Induction: By lipopolysaccharide (LPS) and inflammation; in lung.

Sequence similarities: Belongs to the intercrine alpha (chemokine CxC) family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-GRO-beta/MIP-2 antibody

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