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RANTES Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS691388

RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
RANTES, Polyclonal Antibody
Full Product Name
Rabbit Anti-Mouse RANTES
Product Gene Name
Product Synonym Names
Antigen-Affinity Purified Polyclonal Antibodies Anti-murine RANTES
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Lyophilized
Purity/Purification
Protein A chromatography
Molecular Weight
10,071 Da
Chromosome Location
Chromosome: 11; NC_000077.6 (83525778..83530518, complement). Location: 11 C; 11 50.66 cM
3D Structure
ModBase 3D Structure for P30882
Antibody Generation
Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant murine RANTES (murine RANTES). Anti-murine RANTES specific antibody was purified by affinity chromatography employing immobilized murine RANTES matrix.
Buffer
PBS; pH 7.2
Neutralization
To yield one-half maximal inhibition [ND50] of the biological activity of murine RANTES (100.00 ng/ml), a concentration of 6.0 - 8.0 ug/ml of this antibody is required.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-RANTES antibody
ELISA (EIA), Western Blot (WB), Neutr
Application Notes for anti-RANTES antibody
Western Blot: To detect murine RANTES by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant murine RANTES is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

Other Notes

Small volumes of anti-RANTES antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RANTES purchase

MBS691388 is an antibody targeting RANTES. Also known as Rabbit Anti-Mouse RANTES. Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RANTES. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
C-C motif chemokine 5
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 5
NCBI Official Symbol
Ccl5
NCBI Official Synonym Symbols
SISd; Scya5; RANTES; TCP228; MuRantes
UniProt Protein Name
C-C motif chemokine 5
UniProt Synonym Protein Names
MuRantes; SIS-delta; Small-inducible cytokine A5; T-cell-specific protein RANTES
Protein Family
UniProt Gene Name
Ccl5
UniProt Synonym Gene Names
Scya5
UniProt Entry Name
CCL5_MOUSE
NCBI Protein Information
C-C motif chemokine 5; SIS-delta; small inducible cytokine A5; small-inducible cytokine A5; T-cell-specific protein RANTES

UniProt Comments for RANTES

Function: Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils.

Subcellular location: Secreted.

Tissue specificity: T-cell and macrophage specific.

Sequence similarities: Belongs to the intercrine beta (chemokine CC) family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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