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Persephin (PSP) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS691398

Persephin is a disulfide-linked homodimer neurotrophic factor structurally related to GDNF, Artemin, and Neurturin. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Persephin signals through a… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Persephin (PSP), Polyclonal Antibody
Full Product Name
Rabbit Anti-Human Persephin (PSP)
Product Gene Name
Product Synonym Names
Antigen-Affinity Purified Polyclonal Antibodies Anti-human Persephin
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Lyophilized
Purity/Purification
Affinity chromatography
Molecular Weight
16,600 Da
Chromosome Location
Chromosome: 19; NC_000019.10 (6375294..6375849, complement). Location: 19p13.3
OMIM
602921
3D Structure
ModBase 3D Structure for O60542
Antibody Generation
Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant human Persephin. Anti-Human Persephin specific antibody was purified by affinity chromatography employing immobilized human Persephin matrix.
Buffer
PBS; pH 7.2
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-PSP antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-PSP antibody
Western Blot: To detect human Persephin by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant human Persephin is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions

Other Notes

Small volumes of anti-PSP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PSP purchase

MBS691398 is an antibody targeting PSP. Also known as Rabbit Anti-Human Persephin (PSP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PSP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
persephin
NCBI Official Synonym Full Names
persephin
NCBI Official Symbol
PSPN
NCBI Official Synonym Symbols
PSP
UniProt Protein Name
Persephin
Protein Family
UniProt Gene Name
PSPN
UniProt Synonym Gene Names
PSP
UniProt Entry Name
PSPN_HUMAN
NCBI Protein Information
persephin

NCBI Summary for PSP

The protein encoded by this gene is a neurotrophic factor, belonging to the GDNF family. Neurotrophic factors are important for the proper development and maintenance of the nervous system. These factors promote neuronal survival and can prevent the neuronal degeneration associated with injury, toxin exposure, or neurodegenerative disease. The encoded protein has amino acid similarity to its other family members, glial cell line-derived neurotrophic factor and neurturin. This gene product promotes the survival of ventral midbrain dopaminergic neurons in culture and prevents their degeneration after 6-hydroxydopamine treatment in vivo. [provided by RefSeq, Jul 2008]
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UniProt Comments for PSP

Function: Exhibits neurotrophic activity on mesencephalic dopaminergic and motor neurons.

Subunit structure: Homodimer; disulfide-linked

By similarity.

Subcellular location: Secreted.

Sequence similarities: Belongs to the TGF-beta family. GDNF subfamily.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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