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MIA Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS691423

MIA is the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family; MIA, MIA2, OTOR and TANGO each contain a Src homology-3 (SH3)-like domain. MIA is an autocrine growth regulatory protein… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
MIA, Polyclonal Antibody
Full Product Name
Rabbit Anti-Human MIA
Product Gene Name
Product Synonym Names
Antigen-Affinity Purified Polyclonal Antibodies Anti-human MIA
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Lyophilized
Purity/Purification
Affinity chromatography
Molecular Weight
14,509 Da
Chromosome Location
Chromosome: 19; NC_000019.10 (40775177..40777493). Location: 19q13.2
OMIM
601340
3D Structure
ModBase 3D Structure for Q16674
Antibody Generation
Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hMIA. Anti-Human MIA specific antibody was purified by affinity chromatography employing immobilized hMIA matrix.
Buffer
PBS; pH 7.2
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-MIA antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-MIA antibody
Western Blot: To detect MIA by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant MIA is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

Other Notes

Small volumes of anti-MIA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MIA purchase

MBS691423 is an antibody targeting MIA. Also known as Rabbit Anti-Human MIA. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MIA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
melanoma-derived growth regulatory protein
NCBI Official Synonym Full Names
melanoma inhibitory activity
NCBI Official Symbol
MIA
NCBI Official Synonym Symbols
CD-RAP
UniProt Protein Name
Melanoma-derived growth regulatory protein
UniProt Synonym Protein Names
Melanoma inhibitory activity protein
UniProt Gene Name
MIA
UniProt Entry Name
MIA_HUMAN
NCBI Protein Information
melanoma-derived growth regulatory protein

UniProt Comments for MIA

Function: Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.

Subunit structure: Interacts with FASLG. Interacts with TMIGD2. Ref.9 Ref.10

Subcellular location: Secreted.

Tissue specificity: All malignant melanoma cell lines tested and infrequently in glioma cell lines.

Post-translational modification: May possess two intramolecular disulfide bonds.

Sequence similarities: Belongs to the MIA/OTOR family.Contains 1 SH3 domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-MIA antibody

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