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IGF-1 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS691437

Insulin-like growth factor (IGF)-I (also known as somatomedin C and somatomedin A) and IGF-II (multiplication stimulating activity or MSA) belong to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGF-I and… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
IGF-1, Polyclonal Antibody
Full Product Name
Goat Anti-Mouse IGF-1
Product Gene Name
Product Synonym Names
Antigen-Affinity Purified Polyclonal Antibodies Anti-murine IGF-I
Clonality
Polyclonal
Host
Goat
Species Reactivity
Mouse
Form/Format
Lyophilized
Purity/Purification
Protein A chromatography
Molecular Weight
17,093 Da
Chromosome Location
Chromosome: 10; NC_000076.6 (87858270..87937047). Location: 10 C1; 10 43.7 cM
3D Structure
ModBase 3D Structure for P05017
Antibody Generation
Produced from sera of goats pre-immunized with highly pure (98%) recombinant murine IGF-I. Anti-murine IGF-I specific antibody was purified by affinity chromatography employing immobilized murine IGF-I matrix.
Buffer
PBS; pH 7.2
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-IGF-1 antibody
ELISA (EIA), Western Blot (WB), Neutr
Application Notes for anti-IGF-1 antibody
Western Blot: To detect mIGF-1 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant mIGF-1 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

Other Notes

Small volumes of anti-IGF-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IGF-1 purchase

MBS691437 is an antibody targeting IGF-1. Also known as Goat Anti-Mouse IGF-1. Reactive in Mouse. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for IGF-1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
insulin-like growth factor I isoform 4 preproprotein
NCBI Official Synonym Full Names
insulin-like growth factor 1
NCBI Official Symbol
Igf1
NCBI Official Synonym Symbols
Igf-1; Igf-I; C730016P09Rik
UniProt Protein Name
Insulin-like growth factor I
UniProt Synonym Protein Names
Somatomedin
UniProt Gene Name
Igf1
UniProt Synonym Gene Names
Igf-1; IGF-I
UniProt Entry Name
IGF1_MOUSE
NCBI Protein Information
insulin-like growth factor I; somatomedin

UniProt Comments for IGF-1

Function: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation

By similarity.

Subcellular location: Secreted.

Sequence similarities: Belongs to the insulin family.

Sequence caution: The sequence AAH12409.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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