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NT-3 Mouse Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS691516

NT3 a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Product Overview

Product Name
NT-3, Active Protein
Full Product Name
Mouse NT-3
Product Gene Name
Product Synonym Names
Recombinant Mouse NT-3
Sequence
MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGN SPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL T SENNKLVGW RWIRIDTSCV CALSRKIGRT
Host
E Coli
Species Reactivity
Mouse
Form/Format
Lyophilized fom 0,02% TFA
Purity/Purification
> 97% by SDS-PAGE and RP-HPLC
Molecular Weight
13.6 kDa
Chromosome Location
Chromosome: 6; NC_000072.6 (126101412..126166789, complement). Location: 6 F3; 6 60.45 cM
3D Structure
ModBase 3D Structure for P20181
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Endotoxin Level
< 0.1 ng per ug of NT-3
Biological Activity
The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/ml.

Product Categories/Family for NT-3 active protein

ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.

Other Notes

Small volumes of NT-3 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NT-3 purchase

MBS691516 is an active protein targeting NT-3. Also known as Mouse NT-3. Reactive in Mouse. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for NT-3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
neurotrophin-3 isoform a
NCBI Official Synonym Full Names
neurotrophin 3
NCBI Official Symbol
Ntf3
NCBI Official Synonym Symbols
Nt3; Ntf-3; AI316846; AI835689
UniProt Protein Name
Neurotrophin-3
UniProt Synonym Protein Names
HDNF; Nerve growth factor 2; NGF-2; Neurotrophic factor
UniProt Gene Name
Ntf3
UniProt Synonym Gene Names
Ntf-3; NT-3; NGF-2
UniProt Entry Name
NTF3_MOUSE
NCBI Protein Information
neurotrophin-3; HDNF; NGF-2; neurotrophic factor; nerve growth factor 2

UniProt Comments for NT-3

Function: Seems to promote the survival of visceral and proprioceptive sensory neurons.

Subcellular location: Secreted.

Tissue specificity: Brain and peripheral tissues.

Sequence similarities: Belongs to the NGF-beta family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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