Human CXCL16 Active Protein – Cat# MBS691597

CXCL16 Human Active Protein

Name: CXCL16 Active Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS691597
Price: 305 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS691597

CXCL16 is a member of the CXC chemokine family and signals through the CXCR6 receptor. CXCL16 may play a role in attracting lymphocyte subsets during inflammation and may facilitate certain immune responses. The chemokine domain of CXCL16 contains six… More details

$305 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CXCL16, Active Protein

Full Product Name

Human CXCL16

Product Gene Name

CXCL16 active protein

Product Synonym Names

Recombinant Human CXCL16

Sequence

NEGSVTGSCY CGKRISSDSP PSVQFMNRLR KHLRAYHRCL YYTRFQ LLSW SVCGGNKDPW VQELMSCLDL KECGHAYSGI VAHQKHLLP

Host

E Coli

Species Reactivity

Human

Form/Format

Lyophilized

Purity/Purification

> 98% by SDS-PAGE

Molecular Weight

10.1 kDa

Chromosome Location

Chromosome: 17; NC_000017.11 (4733529..4739928, complement). Location: 17p13

OMIM

605398

3D Structure

ModBase 3D Structure for Q9H2A7

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Endotoxin Level

< 0.1 ng per ug of CXCL16

Biological Activity

Determined by it\'s ability to chemoattract activated lymphocytes using a concentration of 1.0-100.0 ng/ml.

Product Categories/Family for CXCL16 active protein

Cytokines & Growth Factors

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Other Notes

Small volumes of CXCL16 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CXCL16 purchase

MBS691597 is an active protein targeting CXCL16. Also known as Human CXCL16. Reactive in Human. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CXCL16. It may not necessarily be applicable to this product.

NCBI GI #

154816178

NCBI GeneID

58191

NCBI Accession #

NP_001094282.1

UniProt Primary Accession #

Q9H2A7

UniProt Secondary Accession #

Q8TC80; Q96K63; Q9BXD6; Q9H2F6; A0N0N4; A8K7U9; B2RCB0

UniProt Related Accession #

Q9H2A7

GenBank Nucleotide #

NM_001100812.1

NCBI Official Full Name

C-X-C motif chemokine 16

NCBI Official Synonym Full Names

chemokine (C-X-C motif) ligand 16

NCBI Official Symbol

CXCL16

NCBI Official Synonym Symbols

SRPSOX; CXCLG16; SR-PSOX

UniProt Protein Name

C-X-C motif chemokine 16

UniProt Synonym Protein Names

Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; SR-PSOX; Small-inducible cytokine B16; Transmembrane chemokine CXCL16

Protein Family

C-X-C motif chemokine

UniProt Gene Name

CXCL16

UniProt Synonym Gene Names

SCYB16; SRPSOX; SR-PSOX

UniProt Entry Name

CXL16_HUMAN

NCBI Protein Information

C-X-C motif chemokine 16; CXC chemokine ligand 16; small-inducible cytokine B16; transmembrane chemokine CXCL16; scavenger receptor for phosphatidylserine and oxidized low density lipoprotein

UniProt Comments for CXCL16

Function: Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis

By similarity. Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.

Subcellular location: Cell membrane; Single-pass type I membrane protein

Potential. Secreted. Note: Also exists as a soluble form.

Tissue specificity: Expressed in T-cell areas. Expressed in spleen, lymph nodes, lung, kidney, small intestine and thymus. Weak expression in heart and liver and no expression in brain and bone marrow.

Post-translational modification: Glycosylated.

Sequence similarities: Belongs to the intercrine alpha (chemokine CxC) family.

Sequence caution: The sequence AAG34365.1 differs from that shown. Reason: Erroneous initiation. The sequence AAH17588.1 differs from that shown. Reason: Erroneous initiation. The sequence AAH44930.1 differs from that shown. Reason: Erroneous initiation. The sequence ABK41925.1 differs from that shown. Reason: Erroneous initiation. The sequence BAB55078.1 differs from that shown. Reason: Erroneous initiation. The sequence BAF84803.1 differs from that shown. Reason: Erroneous initiation. The sequence BAG37507.1 differs from that shown. Reason: Erroneous initiation.

Research Articles on CXCL16

1. Suggest that expression of transmembrane CXCL16 on surface of plasmacytoid dendritic cell might contribute to high serum IFN-alpha levels seen in patients with Behcet's disease.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CXCL16 active protein

Reference Product	PubMed Publications
CXCR6 active protein	>132 publications with CXCL16 and CXCR6
CXCL10 active protein	>41 publications with CXCL16 and CXCL10
CXCL9 active protein	>26 publications with CXCL16 and CXCL9
CCL5 active protein	>23 publications with CXCL16 and CCL5
CXCL13 active protein	>16 publications with CXCL16 and CXCL13
CCL20 active protein	>14 publications with CXCL16 and CCL20
CXCL11 active protein	>14 publications with CXCL16 and CXCL11
CCR5 active protein	>10 publications with CXCL16 and CCR5
CCR1 active protein	>6 publications with CXCL16 and CCR1

Pathways associated with CXCL16 active protein

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram

Diseases associated with CXCL16 active protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>92 publications with CXCL16 and Inflammation
Necrosis Antibodies	>56 publications with CXCL16 and Necrosis
Neoplasms Antibodies	>56 publications with CXCL16 and Neoplasms
Atherosclerosis Antibodies	>39 publications with CXCL16 and Atherosclerosis
Disease Models, Animal Antibodies	>30 publications with CXCL16 and Disease Models, Animal
Kidney Diseases Antibodies	>29 publications with CXCL16 and Kidney Diseases
Liver Diseases Antibodies	>15 publications with CXCL16 and Liver Diseases
Fibrosis Antibodies	>15 publications with CXCL16 and Fibrosis
Metaplasia Antibodies	>7 publications with CXCL16 and Metaplasia
Breast Neoplasms Antibodies	>7 publications with CXCL16 and Breast Neoplasms

Organs/Tissues associated with CXCL16 active protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>178 publications with CXCL16 and Blood
Vascular Antibodies	>66 publications with CXCL16 and Vascular
Liver Antibodies	>36 publications with CXCL16 and Liver
Kidney Antibodies	>32 publications with CXCL16 and Kidney
Bone Antibodies	>30 publications with CXCL16 and Bone
Lung Antibodies	>24 publications with CXCL16 and Lung
Bone Marrow Antibodies	>19 publications with CXCL16 and Bone Marrow
Heart Antibodies	>19 publications with CXCL16 and Heart
Brain Antibodies	>16 publications with CXCL16 and Brain
Spleen Antibodies	>14 publications with CXCL16 and Spleen