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RANTES (CCL 5) Rat Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS691650

RANTES is a protein which has been shown to be a chemoattractant for peripheral blood monocytes. It appears to selectively attract T cells of the CD4+/CD45RO+ phenotype in vitro. Recombinant Rat RANTES is a 7.9 kDa protein containing 68 amino acid residues. More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
RANTES (CCL 5), Active Protein
Full Product Name
Rat RANTES (CCL 5)
Product Gene Name
RANTES (CCL 5) active protein
Product Synonym Names
Recombinant Rat Fibroblast Growth Factor-2; basic Fibroblast growth factor (bFGF); Heparin binding growth factor-2 (HBGF-2)
Sequence
N-Terminal Sequence: ALPEDGGGAF PP
Host
E Coli
Species Reactivity
Rat
Form/Format
Freeze dried
Purity/Purification
> 98% by SDS-PAGE & silver stain
Molecular Weight
16,34 kDa
Chromosome Location
Chromosome: 10; NC_005109.3 (70373353..70377892, complement). Location: 10q26
3D Structure
ModBase 3D Structure for P13109
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Endotoxin Level
< 0.1ng per ug of rat FGF-2
Buffer
0,5X PBS
Reconstitution Buffer
The rat FGF-2 is supplied in lyophilized form and can be reconstituted with ddH2O at 50 ug/mL. This solution can be diluted into other buffered solutions or stored frozen for future use.

Product Categories/Family for RANTES (CCL 5) active protein

Cytokines & Growth Factors
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.

Testing Data of RANTES (CCL 5) active protein

Rat RANTES (CCL 5) Active Protein – Cat# MBS691650

Testing Data #2 of RANTES (CCL 5) active protein

Rat RANTES (CCL 5) Active Protein, Testing Data #2 – Cat# MBS691650

Product References and Citations for RANTES (CCL 5) active protein

1. Hisaoka K et al, J Biol Chem 286, 2011 2. Florkiewicz RZ et al, Biochem Biophys Res Commun 409, 2011 3. Sun Y et al, J Cell Sci 124, 2011 4. Turner CA et al, Proc Natl Acad Sci 108, 2011 5. Eckenstein FP et al, Biochem Pharmacol 47, 1994 6. el-Husseini AE, Biochim Biophys Acta 1131, 1992 7. Fujimoto K et al, Biochem Biophys Res Commun 180, 1991 8. Shimasaki S et al, Biochem Biophys Res Commun 157, 1988 9. Kurokawa et al, Nucleic Acids Res 16, 1988

Other Notes

Small volumes of RANTES (CCL 5) active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RANTES (CCL 5) purchase

MBS691650 is an active protein targeting RANTES (CCL 5). Also known as Rat RANTES (CCL 5). Reactive in Rat. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for RANTES (CCL 5). It may not necessarily be applicable to this product.

NCBI GI #
1711393
NCBI GeneID
81780
NCBI Accession #
NP_062178.1
UniProt Primary Accession #
P13109
UniProt Related Accession #
P50231
GenBank Nucleotide #
NM_019305.2
NCBI Official Full Name
C-C motif chemokine 5
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 5
NCBI Official Symbol
Ccl5
NCBI Official Synonym Symbols
Scya5; Rantes
UniProt Protein Name
C-C motif chemokine 5
UniProt Synonym Protein Names
SIS-delta; Small-inducible cytokine A5; T-cell-specific protein RANTES
UniProt Gene Name
Ccl5
UniProt Synonym Gene Names
Scya5
UniProt Entry Name
CCL5_RAT
NCBI Protein Information
C-C motif chemokine 5; SIS-delta; small inducible cytokine A5; small-inducible cytokine A5; T-cell-specific protein RANTES; regulated upon activation normal T-cell expressed and secreted

NCBI Summary for RANTES (CCL 5)

may play a role in cellular response to viral infection in testicular somatic cells [RGD, Feb 2006]

UniProt Comments for RANTES (CCL 5)

Function: Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils

By similarity.

Subcellular location: Secreted.

Sequence similarities: Belongs to the intercrine beta (chemokine CC) family.

Research Articles on RANTES (CCL 5)

1. Expression of RANTES and CCR5 in cardiac allografts may play important roles in chronic rejection.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with RANTES (CCL 5) active protein

 Reference Product  PubMed Publications
 Ccl2 active protein  >1285 publications with RANTES (CCL 5) and Ccl2
 Ccl4 active protein  >964 publications with RANTES (CCL 5) and Ccl4
 Ccr5 active protein  >952 publications with RANTES (CCL 5) and Ccr5
 Ccr1 active protein  >302 publications with RANTES (CCL 5) and Ccr1
 Ccr2 active protein  >214 publications with RANTES (CCL 5) and Ccr2
 Ccr3 active protein  >194 publications with RANTES (CCL 5) and Ccr3
 Cxcr3 active protein  >136 publications with RANTES (CCL 5) and Cxcr3
 Ccr4 active protein  >85 publications with RANTES (CCL 5) and Ccr4
 Il8rb active protein  >15 publications with RANTES (CCL 5) and Il8rb
 Ccbp2 active protein  >1 publications with RANTES (CCL 5) and Ccbp2

Pathways associated with RANTES (CCL 5) active protein

 Products by Pathway  Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram

Organs/Tissues associated with RANTES (CCL 5) active protein

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >537 publications with RANTES (CCL 5) and Lung
 Brain Antibodies  >319 publications with RANTES (CCL 5) and Brain
 Heart Antibodies  >158 publications with RANTES (CCL 5) and Heart
 Eye Antibodies  >103 publications with RANTES (CCL 5) and Eye
 Pancreas Antibodies  >29 publications with RANTES (CCL 5) and Pancreas
 Small Intestine Antibodies  >26 publications with RANTES (CCL 5) and Small Intestine
 Uncharacterized Tissue Antibodies  >2 publications with RANTES (CCL 5) and Uncharacterized Tissue
 Pituitary Gland Antibodies  >1 publications with RANTES (CCL 5) and Pituitary Gland
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