Human MIG Active Protein – Cat# MBS691716

MIG (CXCL9) (MIG) Human Active Protein

Name: MIG Active Protein; MIG (CXCL9); Human; MyBioSource
Brand: MyBioSource
SKU: MBS691716
Price: 305 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS691716

MIG, a CXC chemokine, is produced by IFN stimulated monocytes, macrophages and endothelial cells. It signals through the CXCR3 receptor. MIG selectively chemoattracts Th1 lymphocytes, and also exerts other activities including inhibition of tumor growth,… More details

$305 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MIG (CXCL9), Active Protein

Full Product Name

Human MIG (CXCL9)

Product Gene Name

MIG active protein

Product Synonym Names

Recombinant Human MIG

Sequence

TPVVRKGRCS CISTNQGTIH LQSLKDLKQF APSPSCEKIE IIATLK NGVQ TCLNPDSADV KELIKKWEKQ VSQKKKQKNG KKHQKKKVLK V RKSQRSRQK KTT

Host

E Coli

Species Reactivity

Human

Form/Format

Lyophilized

Purity/Purification

>= 98% by SDS-PAGE gel and HPLC analyses.

Preparation and Storage

Stability:
The lyophilized protein is stable at room temperature for 1 month and at 4 degree C for 6 months. Reconstituted working aliquots are stable for 1 week at 2 degree C to 8 degree C and for 12 months at -20 degree C to -80 degree C.

Reconstitution:
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-0.5 mg/m. Do not vortex. This solution can be stored at 2-8 degree C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20 degree C to -80 degree C.

Molecular Weight

11.7 kDa

Chromosome Location

Chromosome: 4; NC_000004.12 (76001470..76007488, complement). Location: 4q21

OMIM

601704

3D Structure

ModBase 3D Structure for Q07325

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Endotoxin Level

< 0.1 ng /ug of protein (<1EU/ug).

Biological Activity

Determined by its ability to chemoattract human peripheral blood T lymphocytes using a concentration range of 10.0-100.0 ng/ml.

Product Categories/Family for MIG active protein

Cytokines & Growth Factors

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Other Notes

Small volumes of MIG active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MIG purchase

MBS691716 is an active protein targeting MIG. Also known as Human MIG (CXCL9). Reactive in Human. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for MIG. It may not necessarily be applicable to this product.

NCBI GI #

4505187

NCBI GeneID

4283

NCBI Accession #

NP_002407.1

UniProt Primary Accession #

Q07325

UniProt Secondary Accession #

Q503B4

UniProt Related Accession #

Q07325

GenBank Nucleotide #

NM_002416.1

NCBI Official Full Name

C-X-C motif chemokine 9

NCBI Official Synonym Full Names

chemokine (C-X-C motif) ligand 9

NCBI Official Symbol

CXCL9

NCBI Official Synonym Symbols

CMK; MIG; Humig; SCYB9; crg-10

UniProt Protein Name

C-X-C motif chemokine 9

UniProt Synonym Protein Names

Gamma-interferon-induced monokine; Monokine induced by interferon-gamma; HuMIG; MIG; Small-inducible cytokine B9

UniProt Gene Name

CXCL9

UniProt Synonym Gene Names

CMK; MIG; SCYB9; HuMIG; MIG

UniProt Entry Name

CXCL9_HUMAN

NCBI Protein Information

C-X-C motif chemokine 9; small-inducible cytokine B9; gamma-interferon-induced monokine; monokine induced by gamma interferon; monokine induced by interferon-gamma

NCBI Summary for MIG

The function of this gene has not been specifically defined; however, it is thought to be involved in T cell trafficking. This gene has been localized to 4q21 with INP10, which is also a member of the chemokine family of cytokines. [provided by RefSeq, Jul 2008]

UniProt Comments for MIG

Function: Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3.

Subcellular location: Secreted.

Induction: By IFNG/IFN-gamma. The induction is enhanced by TNF in dermal fibroblasts and vein endothelial cells.

Sequence similarities: Belongs to the intercrine alpha (chemokine CxC) family.

Research Articles on MIG

1. Our study demonstrated that CXCL9 is associated with tumor burden and aggressiveness of OSCC tumors and serum level of this ligand may be useful as a prognostic indicator

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MIG active protein

Reference Product	PubMed Publications
CXCL10 active protein	>822 publications with MIG and CXCL10
CXCR3 active protein	>427 publications with MIG and CXCR3
CXCL11 active protein	>330 publications with MIG and CXCL11
CCL5 active protein	>215 publications with MIG and CCL5
CCR5 active protein	>81 publications with MIG and CCR5
STAT1 active protein	>59 publications with MIG and STAT1
CCL19 active protein	>35 publications with MIG and CCL19
CCR3 active protein	>29 publications with MIG and CCR3
CXCL13 active protein	>28 publications with MIG and CXCL13
CXCR6 active protein	>10 publications with MIG and CXCR6

Pathways associated with MIG active protein

Products by Pathway	Pathway Diagram
CXCR3-mediated Signaling Events Pathway antibodies	CXCR3-mediated Signaling Events Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram

Diseases associated with MIG active protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>362 publications with MIG and Inflammation
Necrosis Antibodies	>190 publications with MIG and Necrosis
Neoplasms Antibodies	>182 publications with MIG and Neoplasms
Disease Models, Animal Antibodies	>134 publications with MIG and Disease Models, Animal
Lung Diseases Antibodies	>105 publications with MIG and Lung Diseases
Liver Diseases Antibodies	>69 publications with MIG and Liver Diseases
Carcinoma Antibodies	>67 publications with MIG and Carcinoma
Brain Diseases Antibodies	>55 publications with MIG and Brain Diseases
Cardiovascular Diseases Antibodies	>54 publications with MIG and Cardiovascular Diseases
Hypersensitivity Antibodies	>53 publications with MIG and Hypersensitivity

Organs/Tissues associated with MIG active protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>740 publications with MIG and Blood
Lung Antibodies	>151 publications with MIG and Lung
Skin Antibodies	>131 publications with MIG and Skin
Liver Antibodies	>109 publications with MIG and Liver
Brain Antibodies	>91 publications with MIG and Brain
Lymph Node Antibodies	>89 publications with MIG and Lymph Node
Spleen Antibodies	>73 publications with MIG and Spleen
Kidney Antibodies	>63 publications with MIG and Kidney
Heart Antibodies	>48 publications with MIG and Heart
Intestine Antibodies	>33 publications with MIG and Intestine