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Fractalkine (CX3CL1) Rat Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS691796

Fractalkine is a CX3CL chemokine that signals through the CX3CR1 receptor. Fractalkine has been shown to chemoattract monocytes, microglia cells and NK cells. Recombinant rat Fractalkine is an 8.7 kDa protein containing 76 amino acid residues, including the… More details

$305 / 0.005 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Fractalkine (CX3CL1), Active Protein
Full Product Name
Rat Fractalkine (CX3CL1)
Product Gene Name
Product Synonym Names
Recombinant Rat Fractalkine
Sequence
QHLGMTKCNI TCHKMTSPIP VTLLIHYQLN QESCGKRAII LETRQH RHFC ADPKEKWVQD AMKHLDHQTA ALTRNG
Host
E Coli
Species Reactivity
Rat
Form/Format
Lyophilized
Purity/Purification
> 98% by SDS-PAGE and HPLC analysis
Molecular Weight
8.7 kDa
Chromosome Location
Chromosome: 19; NC_005118.3 (10638466..10647951, complement). Location: 19p12
3D Structure
ModBase 3D Structure for O55145
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Endotoxin Level
< 0.1 ng/ug of Fractalkine
Biological Activity
Determined by its ability to chemoattract human monocytes using a concentration range of 5.0-10.0 ng/ml.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.

Other Notes

Small volumes of CX3CL1 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CX3CL1 purchase

MBS691796 is an active protein targeting CX3CL1. Also known as Rat Fractalkine (CX3CL1). Reactive in Rat. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CX3CL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
fractalkine
NCBI Official Synonym Full Names
chemokine (C-X3-C motif) ligand 1
NCBI Official Symbol
Cx3cl1
NCBI Official Synonym Symbols
Cx3c; Scyd1
UniProt Protein Name
Fractalkine
UniProt Synonym Protein Names
C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1
Protein Family
UniProt Gene Name
Cx3cl1
UniProt Synonym Gene Names
Acc1; Fkn; Scyd1
UniProt Entry Name
X3CL1_RAT
NCBI Protein Information
fractalkine; neurotactin; C-X3-C motif chemokine 1; small-inducible cytokine D1; CX3C membrane-anchored chemokine; small inducible cytokine subfamily D, 1

NCBI Summary for CX3CL1

chemokine that binds its receptor CX3CR1; induces chemotaxis and increased intracellular calcium levels in microglia [RGD, Feb 2006]

UniProt Comments for CX3CL1

Function: The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.

Subunit structure: Monomer

By similarity.

Subcellular location: Cell membrane; Single-pass type I membrane protein

By similarity. Processed fractalkine: Secreted

By similarity.

Tissue specificity: Highest levels in brain (neurons). Significant levels in kidney, heart, lung and adrenal gland.

Post-translational modification: A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form.

Sequence similarities: Belongs to the intercrine delta family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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