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IL-17D Human Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS691924

IL-17D is a disulfide-linked homodimer of two 185 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in… More details

$305 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL-17D, Active Protein
Full Product Name
Human IL-17D
Product Gene Name
Product Synonym Names
Recombinant Human IL-17D
Sequence
APRAGRRPAR PRGCADRPEE LLEQLYGRLA AGVLSAFHHT LQLGPR EQAR NASCPAGGRP ADRRFRPPTN LRSVSPWAYR ISYDPARYPR Y LPEAYCLCR GCLTGLFGEE DVRFRSAPVY MPTVVLRRTP ACAGGRS VYT EAYVTIPVGC TCVPEPE kDa DSINSSIDKQ GAKLLLGPND A PAGP
Host
E Coli
Species Reactivity
Human
Form/Format
Lyophilized
Purity/Purification
> 98% by SDS-PAGE and HPLC analysis
Molecular Weight
40.5 kDa
Chromosome Location
Chromosome: 13; NC_000013.11 (20702083..20723100). Location: 13q11
3D Structure
ModBase 3D Structure for Q8TDA2
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Endotoxin Level
< 0.1 ng per ug of IL-17D
Biological Activity
Testing in progress.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.

Other Notes

Small volumes of IL-17D active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL-17D purchase

MBS691924 is an active protein targeting IL-17D. Also known as Human IL-17D. Reactive in Human. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-17D. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
BCRe18/ABL1e3 fusion protein
NCBI Official Synonym Full Names
interleukin 17D
NCBI Official Symbol
IL17D
NCBI Official Synonym Symbols
IL27; IL-27; IL-17D
UniProt Protein Name
BCRe18/ABL1e3 fusion protein
Protein Family
UniProt Gene Name
BCR/ABL fusion
UniProt Entry Name
Q8TDA2_HUMAN
NCBI Protein Information
interleukin-17D; interleukin 27

NCBI Summary for IL-17D

The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. [provided by RefSeq, Jul 2008]
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UniProt Comments for IL-17D

IL17D: Induces expression of IL-6, IL-8, and GM-CSF from endothelial cells. Belongs to the IL-17 family.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 13q11

Cellular Component: extracellular space

Molecular Function: cytokine activity

Biological Process: inflammatory response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with IL-17D active protein

 Products by Pathway  Pathway Diagram
 IL17 Signaling Pathway antibodies  IL17 Signaling Pathway Diagram
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