Human GRO-alpha/MGSA (CXCL1) Active Protein – Cat# MBS692073

GRO-alpha/MGSA (CXCL1) Human Active Protein

Name: GRO-alpha/MGSA (CXCL1) Active Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS692073
Price: 305 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS692073

Human GRO alpha (also known as MGSA) promotes neutrophil chemotaxis and degranulation. It also stimulates mitogenesis in certain human melanoma cells. Human GROa is a 7.8 kDa protein containing 73 amino acid residues More details

$305 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GRO-alpha/MGSA (CXCL1), Active Protein

Full Product Name

Human GRO-alpha/MGSA (CXCL1)

Product Gene Name

GRO-alpha/MGSA (CXCL1) active protein

Product Synonym Names

Recombinant Human GRO/MGSA

Sequence

ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKN GRKA CLNPASPIVK KIIEKMLNSD KSN

Host

E Coli

Species Reactivity

Human

Form/Format

Lyophilized (0.5 x PBS)

Purity/Purification

> 98% by SDS-PAGE and HPLC analyses

Preparation and Storage

Stability:
The lyophilized protein is stable at room temperature for 1 month and at 4°C for 6 months. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.

Reconstitution:
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/m. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Molecular Weight

7.8 kDa

Chromosome Location

Chromosome: 4; NC_000004.12 (73869392..73871302). Location: 4q21

3D Structure

ModBase 3D Structure for P03941

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Endotoxin Level

< 0.1 ng /ug of protein (<1EU/ug).

mRNA RefSeq

NM_001511.3

Biological Activity

Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/ml.

Product Categories/Family for GRO-alpha/MGSA (CXCL1) active protein

Cytokines & Growth Factors

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Other Notes

Small volumes of GRO-alpha/MGSA (CXCL1) active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GRO-alpha/MGSA (CXCL1) purchase

MBS692073 is an active protein targeting GRO-alpha/MGSA (CXCL1). Also known as Human GRO-alpha/MGSA (CXCL1). Reactive in Human. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for GRO-alpha/MGSA (CXCL1). It may not necessarily be applicable to this product.

NCBI GI #

119977

NCBI GeneID

2919

NCBI Accession #

NP_001502.1

UniProt Primary Accession #

P03941

UniProt Related Accession #

P09341

NCBI Official Full Name

Ferredoxin

NCBI Official Synonym Full Names

chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)

NCBI Official Symbol

CXCL1

NCBI Official Synonym Symbols

FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a

UniProt Protein Name

Ferredoxin

UniProt Entry Name

FER_ALIAC

NCBI Protein Information

growth-regulated alpha protein; MGSA alpha; GRO-alpha(1-73); C-X-C motif chemokine 1; fibroblast secretory protein; neutrophil-activating protein 3; melanoma growth stimulatory activity alpha; GRO1 oncogene (melanoma growth-stimulating activity); GRO1 oncogene (melanoma growth stimulating activity, alpha)

NCBI Summary for GRO-alpha/MGSA (CXCL1)

This gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signal through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Jan 2012]

UniProt Comments for GRO-alpha/MGSA (CXCL1)

Function: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

Cofactor: Binds 1 3Fe-4S cluster

Probable.Binds 1 4Fe-4S cluster

Probable.

Sequence similarities: Contains 2 4Fe-4S ferredoxin-type domains.

Research Articles on GRO-alpha/MGSA (CXCL1)

1. findings of the current study suggest a broad involvement of the chemokine GRO-alpha/CXCR2 system in Sjogren's syndrome pathogenesis that is mediated by the involvement of ADAM17

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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