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FGF-6 Human Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS692129

FGF-6 is a secreted heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation… More details

$305 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FGF-6, Active Protein
Full Product Name
Human FGF-6
Product Gene Name
Product Synonym Names
Recombinant Human FGF-6
Sequence
GTRANNTLL DSRGWGTLLS RSRAGLAGEI AGVNWESGYL VGIKRQR RLY CNVGIGFHLQ VLPDGRISGT HEENPYSLLE ISTVERGVVS LF GVRSALFV AMNSKGRLYA TPSFQEECKF RETLLPNNYN AYESDLYQ GT YIALSKYGRV KRGSKVSPIM TVTHFLPRI
Host
E Coli
Species Reactivity
Human
Form/Format
Lyophilized
Purity/Purification
> 95% by SDS-PAGE and HPLC analyses
Molecular Weight
18.7 kDa
Chromosome Location
Chromosome: 12; NC_000012.12 (4434142..4445614, complement). Location: 12p13
OMIM
134921
3D Structure
ModBase 3D Structure for P10767
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Endotoxin Level
< 0.1 ng per of FGF-6
Biological Activity
The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is <= 0.5 ng/ml, corresponding to a specific activity of >= 2 x 106 units/mg.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.

Other Notes

Small volumes of FGF-6 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FGF-6 purchase

MBS692129 is an active protein targeting FGF-6. Also known as Human FGF-6. Reactive in Human. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for FGF-6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
fibroblast growth factor 6
NCBI Official Synonym Full Names
fibroblast growth factor 6
NCBI Official Symbol
FGF6
NCBI Official Synonym Symbols
HST2; HBGF-6
UniProt Protein Name
Fibroblast growth factor 6
UniProt Synonym Protein Names
Heparin secretory-transforming protein 2; HST-2; HSTF-2; Heparin-binding growth factor 6
UniProt Gene Name
FGF6
UniProt Synonym Gene Names
HST2; HSTF2; FGF-6; HST-2; HSTF-2; HBGF-6
UniProt Entry Name
FGF6_HUMAN
NCBI Protein Information
fibroblast growth factor 6; FGF-6; HST-2; HSTF-2; heparin-binding growth factor 6; heparin secretory-transforming protein 2

NCBI Summary for FGF-6

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation. [provided by RefSeq, Jul 2008]
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UniProt Comments for FGF-6

Function: Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration. Ref.6

Subunit structure: Interacts with FGFR1, FGFR2 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Ref.6

Subcellular location: Secreted › extracellular space.

Tissue specificity: Leukemia cell lines with platelet/ megakaryocytic differentiation potential.

Sequence similarities: Belongs to the heparin-binding growth factors family.

Sequence caution: The sequence CAA40359.1 differs from that shown. Reason: Erroneous initiation. The sequence CAA40360.1 differs from that shown. Reason: Erroneous initiation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with FGF-6 active protein

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