• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

I-309 (CCL1) Human Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS692146

Human I-309 is an 8.5 kDa protein containing 74 amino acid residues. I-309 is a small glycoprotein secreted by activated T lymphocytes and structurally related to other CC chemokines. More details

$305 / 0.002 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
I-309 (CCL1), Active Protein
Full Product Name
Human I-309 (CCL1)
Product Synonym Names
Recombinant Human I-309
Sequence
SKSMQVPFSR CCFSFAEQEI PLRAILCYRN TSSICSNEGL IFKLKR GKEA CALDTVGWVQ RHRKMLRHCP SKRK
Host
E Coli
Species Reactivity
Human
Form/Format
Lyophilized
Purity/Purification
> 99 % (SDS-PAGE, HPLC)
Molecular Weight
8.5 kDa
Chromosome Location
Chromosome: 17; NC_000017.11 (34360328..34363233, complement). Location: 17q12
OMIM
182281
3D Structure
ModBase 3D Structure for P22362
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Endotoxin Level
< 0.1 ng/ug of I-309
Biological Activity
Determined by its ability to chemoattract total human T cell population using a concentration range of 10.0-100.0 ng/ml.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.

Other Notes

Small volumes of I-309 (CCL1) active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for I-309 (CCL1) purchase

MBS692146 is an active protein targeting I-309 (CCL1). Also known as Human I-309 (CCL1). Reactive in Human. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for I-309 (CCL1). It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
C-C motif chemokine 1
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 1
NCBI Official Symbol
CCL1
NCBI Official Synonym Symbols
P500; SISe; TCA3; I-309; SCYA1
UniProt Protein Name
C-C motif chemokine 1
UniProt Synonym Protein Names
Small-inducible cytokine A1; T lymphocyte-secreted protein I-309
UniProt Gene Name
CCL1
UniProt Synonym Gene Names
SCYA1
UniProt Entry Name
CCL1_HUMAN
NCBI Protein Information
C-C motif chemokine 1; inflammatory cytokine I-309; T lymphocyte-secreted protein I-309; small inducible cytokine A1 (I-309, homologous to mouse Tca-3)

NCBI Summary for I-309 (CCL1)

This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Jul 2013]
Show more

UniProt Comments for I-309 (CCL1)

Function: Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8. Ref.7

Subunit structure: Monomer.

Subcellular location: Secreted.

Induction: By phorbol myristate acetate (PMA).

Sequence similarities: Belongs to the intercrine beta (chemokine CC) family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with I-309 (CCL1) active protein

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >22 publications with I-309 (CCL1) and Lung
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000