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VE-STATIN/EGFL-7 Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS692160

EGFL7 (VE-Statin) is an ~ 30 kDa secreted protein that contains an Emilin-like (EMI) domain (a multimerization motif), and two epidermal growth factor (EGF) domains, one of which binds calcium. Based on these domains, it has been hypothesized that EGFL7 may… More details

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Product Overview

Online Datasheet in PDF
Product Name
VE-Statin/EGFL-7, Recombinant Protein
Full Product Name
Human VE-Statin/EGFL7
Product Synonym Names
Recombinant Human VE-Statin/EGFL7; EGF-like protein 7; Vascular endothelial statin; Multiple EGF-like domains protein 7
Host
Insect Cells
Species Reactivity
Human
Form/Format
Lyophilized
Purity/Purification
> 95% by SDS-PAGE & silver stain
Preparation and Storage
Lyophilized samples are stable for greater than six months at -20 degree C to -70 degree C. Reconstituted EGFL7 should be stored in working aliquots at -20 degree C. Avoid repeated freeze-thaw cycles!
Molecular Weight
22,75 kDa
Chromosome Location
Chromosome: 9; NC_000009.12 (136658856..136672678). Location: 9q34.3
OMIM
608582
3D Structure
ModBase 3D Structure for Q9UHF1
Buffer
Water
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.

Product References and Citations for VE-Statin/EGFL-7 recombinant protein

1. Schmidt MH et al, Nat Cell Biol 11:873, 2009 2. Nikolic et al, Blood 121:3041, 2013 3. Schmidt MH et al, Development 134: 2913-2923 (2007) 4. Socin F et al, EMBO Journal 22: 5700-5711 (2003) 5. Picuric S et al, Protein Expression and Purification 68: 1-6 (2009) 6. Caetano B et al, Protein Expression and Purification 46: 136-142 (2006) 7. Nichol D & Stuhlmann H, Blood 119:1345-1352 (2012)

Other Notes

Small volumes of VE-Statin/EGFL-7 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VE-Statin/EGFL-7 purchase

MBS692160 is a recombinant protein targeting VE-Statin/EGFL-7. Also known as Human VE-Statin/EGFL7. Reactive in Human. Host: Insect Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for VE-Statin/EGFL-7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
epidermal growth factor-like protein 7
NCBI Official Synonym Full Names
EGF-like-domain, multiple 7
NCBI Official Symbol
EGFL7
NCBI Official Synonym Symbols
NEU1; ZNEU1; VE-STATIN; RP11-251M1.2
UniProt Protein Name
Epidermal growth factor-like protein 7
UniProt Synonym Protein Names
Multiple epidermal growth factor-like domains protein 7; Multiple EGF-like domains protein 7; NOTCH4-like protein; Vascular endothelial statin; VE-statin; Zneu1
UniProt Gene Name
EGFL7
UniProt Synonym Gene Names
MEGF7; EGF-like protein 7; Multiple EGF-like domains protein 7; VE-statin
UniProt Entry Name
EGFL7_HUMAN
NCBI Protein Information
epidermal growth factor-like protein 7; EGF-like protein 7; NOTCH4-like protein; vascular endothelial statin; multiple EGF-like domains protein 7; multiple epidermal growth factor-like domains protein 7

NCBI Summary for VE-Statin/EGFL-7

This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
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UniProt Comments for VE-Statin/EGFL-7

Function: Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cells adhesion to the substrate in vitro

By similarity.

Subcellular location: Secreted

By similarity.

Sequence similarities: Contains 2 EGF-like domains.Contains 1 EMI domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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