Mouse TARC Active Protein – Cat# MBS692551

TARC (CCL17) (TARC) Mouse Active Protein

Name: TARC Active Protein; TARC (CCL17); Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS692551
Price: 320 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS692551

TARC, a CC chemokine, is predominantly produced by dendritic cells in the thymus, and signals through the CCR4 receptor. TARC is chemotactic towards T cells. Recombinant Murine TARC (CCL17) is an 7.9 kDa protein containing 70 amino acid residues, including… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

TARC (CCL17), Active Protein

Full Product Name

Mouse TARC (CCL17)

Product Gene Name

TARC active protein

Product Synonym Names

Thymus and Activation Regulated Chemokine; CCL17; ABCD-2

Sequence

ARATNVGREC CLDYFKGAIP IRKLVSWYKT SVECSRDAIV FLTVQGKLIC ADPKDKHVKK AIRLVKNPRP

Host

E Coli

Species Reactivity

Mouse

Form/Format

Lyophilized

Purity/Purification

>= 98% by SDS-PAGE gel and HPLC analyses

Molecular Weight

7.9 kDa

3D Structure

ModBase 3D Structure for Q9WUZ6

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Endotoxin Level

< 0.1 ng/ug of protein (<1EU/ug)

Biological Activity

Determined by its ability to chemoattract murine BW5147.3 thymic lymphoma cells. The ED50 for this effect is 10-40 ng/ml.

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Other Notes

Small volumes of TARC active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TARC purchase

MBS692551 is an active protein targeting TARC. Also known as Mouse TARC (CCL17). Reactive in Mouse. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for TARC. It may not necessarily be applicable to this product.

NCBI GI #

5102778

NCBI GeneID

20295

NCBI Accession #

CAB45256.1

UniProt Primary Accession #

Q9WUZ6

GenBank Nucleotide #

NM_011332.3

NCBI Official Full Name

thymus and activation-regulated chemokine

NCBI Official Synonym Full Names

chemokine (C-C motif) ligand 17

NCBI Official Symbol

Ccl17

NCBI Official Synonym Symbols

Tarc; Abcd-2; Scya17; Scya17l

UniProt Protein Name

CC chemokine ABCD-2

UniProt Gene Name

Ccl17

UniProt Synonym Gene Names

ABCD-2

UniProt Entry Name

Q9WUZ6_MOUSE

NCBI Protein Information

C-C motif chemokine 17

Research Articles on TARC

1. Basal expression of Ccl17 in hippocampal neurons was strongly enhanced by peripheral challenge with lipopolysaccharide (LPS). LPS-mediated induction of Ccl17 in the hippocampus was dependent on local tumor necrosis factor signaling, whereas upregulation of Ccl22 required granulocyte-macrophage colony-stimulating factorCCL17 deficiency resulted in a diminished microglia density under homeostatic and inflammatory conditions

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with TARC active protein

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram

Diseases associated with TARC active protein

Disease Name	Pubmed Publications
Hypersensitivity Antibodies	>257 publications with TARC and Hypersensitivity
Inflammation Antibodies	>234 publications with TARC and Inflammation
Skin Diseases Antibodies	>199 publications with TARC and Skin Diseases
Dermatitis, Atopic Antibodies	>141 publications with TARC and Dermatitis, Atopic
Lung Diseases Antibodies	>134 publications with TARC and Lung Diseases
Asthma Antibodies	>112 publications with TARC and Asthma
Respiratory Hypersensitivity Antibodies	>107 publications with TARC and Respiratory Hypersensitivity
Necrosis Antibodies	>93 publications with TARC and Necrosis
Immunoproliferative Disorders Antibodies	>62 publications with TARC and Immunoproliferative Disorders
Fibrosis Antibodies	>28 publications with TARC and Fibrosis

Organs/Tissues associated with TARC active protein

Organ/Tissue Name	Pubmed Publications
Thymus Antibodies	>286 publications with TARC and Thymus
Mixed Antibodies	>10 publications with TARC and Mixed
Stomach Antibodies	>6 publications with TARC and Stomach
Pancreas Antibodies	>2 publications with TARC and Pancreas
Mammary Gland Antibodies	>1 publications with TARC and Mammary Gland