Goat Anti-CCL24 Polyclonal Antibody – Cat# MBS695294

Eotaxin-2 (CCL24) Antibody – Goat Polyclonal

Name: CCL24 Antibody; Polyclonal; Goat; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS695294
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS695294

Produced from sera of goats pre-immunized with highly pure (>98%) recombinant mEotaxin-2. Anti-Murine Eotaxin-2 specific antibody was purified by affinity chromatography and then biotinylated. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Eotaxin-2 (Ccl24), Polyclonal Antibody

Full Product Name

Biotinylated Anti-mEotaxin-2

Product Gene Name

anti-Ccl24 antibody

Product Synonym Names

Biotinylated Anti-Murine Eotaxin-2

Clonality

Polyclonal

Host

Goat

Species Reactivity

Mouse

Form/Format

Biotin

Preparation and Storage

At -20 degree C

Molecular Weight

12,871 Da

3D Structure

ModBase 3D Structure for Q9JKC0

Immunogen

Recombinant Murine Eotaxin-2

Applications Tested/Suitable for anti-Ccl24 antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-Ccl24 antibody

Direct Detection: To detect mEotaxin-2 by direct ELISA (using 100 mul/well antibody solution) a concentration of 0.25 - 1.0 mug/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2 - 0.4 ng/well of recombinant mEotaxin-2.

Sandwich ELISA: To detect mEotaxin-2 by sandwich ELISA (using 100 mul/well antibody solution) a concentration of 0.25 - 1.0 mug/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with Polyclonal Anti-Murine Eotaxin-2 as a capture antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant mEotaxin-2.

Western Blot: To detect mEotaxin-2 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant mEotaxin-2 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

Other Notes

Small volumes of anti-Ccl24 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Ccl24 purchase

MBS695294 is an antibody targeting Ccl24. Also known as Biotinylated Anti-mEotaxin-2. Reactive in Mouse. Host: Goat.

Additional Details

NCBI/Uniprot data below describe general gene information for Ccl24. It may not necessarily be applicable to this product.

NCBI GI #

13431902

NCBI GeneID

56221

NCBI Accession #

Q9JKC0.1

UniProt Primary Accession #

Q9JKC0

UniProt Related Accession #

Q9JKC0

NCBI Official Full Name

C-C motif chemokine 24

NCBI Official Synonym Full Names

chemokine (C-C motif) ligand 24

NCBI Official Symbol

Ccl24

NCBI Official Synonym Symbols

CKb-6; MPIF-2; Scya24

UniProt Protein Name

C-C motif chemokine 24

UniProt Synonym Protein Names

Eosinophil chemotactic protein 2; Eotaxin-2; Small-inducible cytokine A24

Protein Family

C-C motif chemokine

UniProt Gene Name

Ccl24

UniProt Synonym Gene Names

Scya24

UniProt Entry Name

CCL24_MOUSE

NCBI Protein Information

C-C motif chemokine 24; eotaxin-2; CC chemokine CCL24; small inducible cytokine A24; small-inducible cytokine A24; eosinophil chemotactic protein 2

UniProt Comments for Ccl24

CCL24: Chemotactic for resting T-lymphocytes, and eosinophils. Has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. Is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Binds to CCR3. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis

Cellular Component: extracellular space; extracellular region

Molecular Function: chemokine activity; cytokine activity

Biological Process: regulation of cell shape; positive regulation of angiogenesis; positive regulation of actin filament polymerization; eosinophil chemotaxis; immune response; cytoskeleton organization and biogenesis; positive regulation of endothelial cell proliferation; chemotaxis; inflammatory response; positive regulation of cell migration; positive regulation of inflammatory response

Research Articles on Ccl24

1. Autologous transfer of peritoneal macrophages in to the airways of asthmatic mice reduces eotaxin production.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Ccl24 antibody

Products by Pathway	Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram

Diseases associated with anti-Ccl24 antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>113 publications with Ccl24 and Inflammation
Immune System Diseases Antibodies	>99 publications with Ccl24 and Immune System Diseases
Hypersensitivity Antibodies	>93 publications with Ccl24 and Hypersensitivity
Asthma Antibodies	>91 publications with Ccl24 and Asthma
Respiratory Tract Diseases Antibodies	>89 publications with Ccl24 and Respiratory Tract Diseases
Lung Diseases Antibodies	>81 publications with Ccl24 and Lung Diseases
Respiratory Hypersensitivity Antibodies	>65 publications with Ccl24 and Respiratory Hypersensitivity
Necrosis Antibodies	>27 publications with Ccl24 and Necrosis
Skin Diseases Antibodies	>24 publications with Ccl24 and Skin Diseases
Dermatitis Antibodies	>18 publications with Ccl24 and Dermatitis

Organs/Tissues associated with anti-Ccl24 antibody

Organ/Tissue Name	Pubmed Publications
Intestine Antibodies	>9 publications with Ccl24 and Intestine
Spleen Antibodies	>8 publications with Ccl24 and Spleen
Thymus Antibodies	>5 publications with Ccl24 and Thymus
Embryonic Tissue Antibodies	>2 publications with Ccl24 and Embryonic Tissue