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Exodus-2 (GM10591) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS695344

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant mExodus-2. Anti-Murine Exodus-2 specific antibody was purified by affinity chromatography employing immobilized mExodus-2 matrix. More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Product Name
Exodus-2 (Gm10591), Polyclonal Antibody
Full Product Name
Anti-murine Exodus-2
Product Gene Name
anti-Gm10591 antibody
Product Synonym Names
Anti-Murine Exodus-2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Mouse
Form/Format
Purified
Preparation and Storage
At -20 degree C
Molecular Weight
14,584 Da
3D Structure
ModBase 3D Structure for P86792
Immunogen
Recombinant Murine Exodus-2
Applications Tested/Suitable for anti-Gm10591 antibody
Neutralization, ELISA (EIA), Western Blot (WB)
Application Notes for anti-Gm10591 antibody
Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of mExodus-2 (100.0 ng/ml), a concentration of 4.0-8.0 ug/ml of this antibody is required.

Sandwich ELISA: To detect mExodus-2 by sandwich ELISA (using 100 mul/well antibody solution) a concentration of 0.5 - 2.0 mug/ml of this antibody is required. This antigen affinity purified antibody, in conjunction with Biotinylated Anti-Murine Exodus-2 as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant mExodus-2.

Western Blot: To detect mExodus-2 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 ug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant mExodus-2 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

Other Notes

Small volumes of anti-Gm10591 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Gm10591 purchase

MBS695344 is an antibody targeting Gm10591. Also known as Anti-murine Exodus-2. Reactive in Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for Gm10591. It may not necessarily be applicable to this product.

NCBI GI #
317552256
NCBI GeneID
100504239
NCBI Accession #
P86792.1
UniProt Primary Accession #
P86792
UniProt Secondary Accession #
O09002; O09006; P84443; Q5M8M5; Q91V84
NCBI Official Full Name
C-C motif chemokine 21b
NCBI Official Synonym Full Names
predicted gene 10591
NCBI Official Symbol
Gm10591
NCBI Official Synonym Symbols
ENSMUSG00000073869
UniProt Protein Name
C-C motif chemokine 21b
UniProt Synonym Protein Names
6Ckine; Beta-chemokine exodus-2; Small-inducible cytokine A21b; Thymus-derived chemotactic agent 4; TCA4
Protein Family
C-C motif chemokine
UniProt Gene Name
Ccl21b
UniProt Synonym Gene Names
Scya21; Scya21b; TCA4
UniProt Entry Name
CC21B_MOUSE
NCBI Protein Information
predicted gene 10591

UniProt Comments for Gm10591

CCL21b: Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Potent mesangial cell chemoattractant. Shows preferential activity towards naive T- cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Chemokine; Motility/polarity/chemotaxis

Cellular Component: external side of plasma membrane

Molecular Function: chemokine receptor binding; chemokine activity

Biological Process: negative regulation of myeloid cell differentiation; leukocyte chemotaxis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-Gm10591 antibody

 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
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