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RANTES Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS695407

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant Rat RANTES. Anti-Rat RANTES specific antibody was purified by affinity chromatography and then biotinylated. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
RANTES, Polyclonal Antibody
Full Product Name
Biotinylated Anti-rat RANTES
Product Gene Name
anti-RANTES antibody
Product Synonym Names
Biotinylated Anti-Rat RANTES
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Rat
Form/Format
Biotin
Preparation and Storage
At -20 degree C
Molecular Weight
10,170 Da
3D Structure
ModBase 3D Structure for P50231
Immunogen
Recombinant Rat RANTES
Applications Tested/Suitable for anti-RANTES antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-RANTES antibody
Direct Detection: To detect Rat RANTES by direct ELISA (using 100 mul/well antibody solution) a concentration of 0.25 - 1.0 mug/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2 - 0.4 ng/well of recombinant Rat RANTES.

Sandwich ELISA: To detect Rat RANTES by sandwich ELISA (using 100 mul/well antibody solution) a concentration of 0.25 - 1.0 mug/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with Polyclonal Anti-Rat RANTES as a capture antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant Rat RANTES.

Western Blot: To detect Rat RANTES by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 ug /ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant Rat RANTES is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

Other Notes

Small volumes of anti-RANTES antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RANTES purchase

MBS695407 is an antibody targeting RANTES. Also known as Biotinylated Anti-rat RANTES. Reactive in Rat. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RANTES. It may not necessarily be applicable to this product.

NCBI GI #
1711393
NCBI GeneID
81780
NCBI Accession #
P50231.1
UniProt Primary Accession #
P50231
UniProt Related Accession #
P50231
NCBI Official Full Name
C-C motif chemokine 5
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 5
NCBI Official Symbol
Ccl5
NCBI Official Synonym Symbols
Scya5; Rantes
UniProt Protein Name
C-C motif chemokine 5
UniProt Synonym Protein Names
SIS-delta; Small-inducible cytokine A5; T-cell-specific protein RANTES
Protein Family
C-C motif chemokine
UniProt Gene Name
Ccl5
UniProt Synonym Gene Names
Scya5
UniProt Entry Name
CCL5_RAT
NCBI Protein Information
C-C motif chemokine 5; SIS-delta; small inducible cytokine A5; small-inducible cytokine A5; T-cell-specific protein RANTES; regulated upon activation normal T-cell expressed and secreted

NCBI Summary for RANTES

may play a role in cellular response to viral infection in testicular somatic cells [RGD, Feb 2006]

UniProt Comments for RANTES

Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells.
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Research Articles on RANTES

1. Expression of RANTES and CCR5 in cardiac allografts may play important roles in chronic rejection.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RANTES antibody

 Reference Product  PubMed Publications
 Ccl2 antibody  >1367 publications with RANTES and Ccl2
 Ccl4 antibody  >990 publications with RANTES and Ccl4
 Ccr5 antibody  >987 publications with RANTES and Ccr5
 Ccr1 antibody  >308 publications with RANTES and Ccr1
 Ccr2 antibody  >222 publications with RANTES and Ccr2
 Ccr3 antibody  >195 publications with RANTES and Ccr3
 Cxcr3 antibody  >144 publications with RANTES and Cxcr3
 Ccr4 antibody  >89 publications with RANTES and Ccr4
 Il8rb antibody  >16 publications with RANTES and Il8rb
 Ccbp2 antibody  >1 publications with RANTES and Ccbp2

Pathways associated with anti-RANTES antibody

 Products by Pathway  Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chagas Disease (American Trypanosomiasis) Pathway antibodies  Chagas Disease (American Trypanosomiasis) Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram

Organs/Tissues associated with anti-RANTES antibody

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >563 publications with RANTES and Lung
 Brain Antibodies  >339 publications with RANTES and Brain
 Heart Antibodies  >176 publications with RANTES and Heart
 Eye Antibodies  >113 publications with RANTES and Eye
 Pancreas Antibodies  >32 publications with RANTES and Pancreas
 Small Intestine Antibodies  >28 publications with RANTES and Small Intestine
 Pituitary Gland Antibodies  >2 publications with RANTES and Pituitary Gland
 Uncharacterized Tissue Antibodies  >2 publications with RANTES and Uncharacterized Tissue
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