Rabbit Anti-BD-4 Polyclonal Antibody – Cat# MBS695493

BD-4 Antibody – Rabbit Polyclonal

Name: BD-4 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS695493
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS695493

Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hBD-4 (Human Beta Defensin-4). Anti-hBD-4 specific antibody was purified by affinity chromatography and then biotinylated. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

BD-4, Polyclonal Antibody

Full Product Name

Biotinylated anti-hBD-4

Product Gene Name

anti-BD-4 antibody

Product Synonym Names

Biotinylated Anti-Human BD-4

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Human

Form/Format

Biotin

Preparation and Storage

At -20 degree C

Molecular Weight

8,526 Da

3D Structure

ModBase 3D Structure for Q8WTQ1

Immunogen

Recombinant Human BD-4

Applications Tested/Suitable for anti-BD-4 antibody

ELISA (EIA), Western Blot (WB)

Application Notes for anti-BD-4 antibody

Direct Detection: To detect hBD-4 by direct ELISA (using 100 mul/well antibody solution) a concentration of 0.25 - 1.0 mug/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hBD-4.

Sandwich ELISA: To detect hBD-4 by sandwich ELISA (using 100 mul/well antibody solution) a concentration of 0.25 - 1.0 mug/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with Polyclonal Anti-Human BD-4 as a capture antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hBD-4.

Western Blot: To detect hBD-4 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 mug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hBD-4 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.

Other Notes

Small volumes of anti-BD-4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BD-4 purchase

MBS695493 is an antibody targeting BD-4. Also known as Biotinylated anti-hBD-4. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for BD-4. It may not necessarily be applicable to this product.

NCBI GI #

118572637

NCBI GeneID

140596

NCBI Accession #

Q8WTQ1.2

UniProt Primary Accession #

Q8WTQ1

UniProt Secondary Accession #

Q496I2; Q496I3; Q496I4

UniProt Related Accession #

Q8WTQ1

NCBI Official Full Name

Beta-defensin 104

NCBI Official Synonym Full Names

defensin, beta 104A

NCBI Official Symbol

DEFB104A

NCBI Official Synonym Symbols

BD-4; DEFB4; hBD-4; DEFB-4; DEFB104

UniProt Protein Name

Beta-defensin 104

UniProt Synonym Protein Names

Beta-defensin 4; BD-4; DEFB-4; hBD-4; Defensin, beta 104

UniProt Gene Name

DEFB104A

UniProt Synonym Gene Names

DEFB104; DEFB4; BD-4; DEFB-4; hBD-4

UniProt Entry Name

D104A_HUMAN

NCBI Protein Information

beta-defensin 104; defensin, beta 4

NCBI Summary for BD-4

Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 104, DEFB104A and DEFB104B, in head-to-head orientation. This gene, DEFB104A, represents the more centromeric copy. [provided by RefSeq, Oct 2014]

UniProt Comments for BD-4

defensin, beta 4: Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103. Belongs to the beta-defensin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 8p23.1

Cellular Component: cell surface; extracellular region

Biological Process: defense response to bacterium; innate immune response

Research Articles on BD-4

1. Beta-defensin 104 displays antimicrobial activity against S. carnosus, E. coli, S. cerevisiae, and P. aeruginosa (strong).

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-BD-4 antibody

Reference Product	PubMed Publications
DEFB103A antibody	>2 publications with BD-4 and DEFB103A

Pathways associated with anti-BD-4 antibody

Products by Pathway	Pathway Diagram
Beta Defensins Pathway antibodies	Beta Defensins Pathway Diagram
Defensins Pathway antibodies	Defensins Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram