Rabbit Anti-IFNb Polyclonal Antibody – Cat# MBS2001735

Interferon Beta (IFNb) Antibody – Rabbit Polyclonal

Name: IFNb Antibody; Polyclonal; Rabbit; Dog-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2001735
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2001735

MBS2001735 is an antibody targeting IFNb. Also known as Biotin-Linked Antibody to Interferon Beta (IFNb). Reactive in Dog. Host: Rabbit. More details

$230 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Interferon Beta (IFNb), Polyclonal Antibody

Full Product Name

Biotin-Linked Antibody to Interferon Beta (IFNb)

Product Gene Name

anti-IFNb antibody

Clonality

Polyclonal

Host

Rabbit

Species Reactivity

Dog

Form/Format

Supplied as solution form in PBS, pH7.4, 50% glycerol 0.05% Proclin-300.

Purity/Purification

Antigen-specific Affinity Chromatography.

Concentration

0.31mg/ml (lot specific)

Preparation and Storage

Storage:
Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 24 months.

Stability Test:
thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Matching Pairs

Biotin Conjugated Antibody: IFNb (MBS2001735)
Immunogen: IFNb (MBS2011937)

Matching Pairs

Unconjugated Antibody: IFNb (MBS2002605)
Biotin Conjugated Antibody: IFNb (MBS2001735)

Chromosome Location

Chromosome: 9; NC_000009.11 (21077104..21077943, complement). Location: 9p21

OMIM

147640

3D Structure

ModBase 3D Structure for P01574

Supply Chain Verification

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Source

Antibody labeling

Label

Biotin

Unconjugated Antibody

MBS2002605

Traits

Liquid

Immunogen

Recombinant IFNb (Ala21~Asn186) expressed in E.coli ( MBS2011937 ).

Product Categories/Family for anti-IFNb antibody

Biotin Antibody

ISO Certification

Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.

Applications Tested/Suitable for anti-IFNb antibody

Western Blot (WB); Immunohistochemistry (IHC); Immunocytochemistry (ICC);

Application Notes for anti-IFNb antibody

Western blotting: 0.5-2ug/mL
Immunohistochemistry: 5-20ug/mL
Immunocytochemistry: 5-20ug/mL
Optimal working dilutions must be determined by end user.

Other Notes

Small volumes of anti-IFNb antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IFNb. It may not necessarily be applicable to this product.

NCBI GI #

4504603

NCBI GeneID

3456

NCBI Accession #

NP_002167.1

UniProt Primary Accession #

P01574

UniProt Related Accession #

P01574

GenBank Nucleotide #

NM_002176.2

NCBI Official Full Name

interferon beta

NCBI Official Synonym Full Names

interferon, beta 1, fibroblast

NCBI Official Symbol

IFNB1

NCBI Official Synonym Symbols

IFB; IFF; IFNB

UniProt Protein Name

Interferon beta

UniProt Synonym Protein Names

Fibroblast interferon

Protein Family

Interferon

UniProt Gene Name

IFNB1

UniProt Synonym Gene Names

IFB; IFNB; IFN-beta

UniProt Entry Name

IFNB_HUMAN

NCBI Protein Information

interferon beta; IFN-beta; fibroblast interferon

UniProt Comments for IFNb

IFNB1: Has antiviral, antibacterial and anticancer activities. Belongs to the alpha/beta interferon family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9p21

Cellular Component: extracellular space; extracellular region

Molecular Function: interferon-alpha/beta receptor binding; cytokine activity

Biological Process: B cell proliferation; adaptive immune response; cytokine and chemokine mediated signaling pathway; response to virus; regulation of MHC class I biosynthetic process; natural killer cell activation; negative regulation of T cell differentiation; humoral immune response; T cell activation during immune response; cell surface receptor linked signal transduction; response to exogenous dsRNA; negative regulation of viral genome replication; B cell differentiation; defense response to bacterium; positive regulation of innate immune response; natural killer cell activation during immune response; innate immune response; positive regulation of transcription from RNA polymerase II promoter; blood coagulation; defense response to virus; B cell activation during immune response; positive regulation of peptidyl-serine phosphorylation of STAT protein

Research Articles on IFNb

1. Herpes simplex virus 1 US3 hyperphosphorylates IRF3 and inhibits beta interferon production.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IFNb antibody

Reference Product	PubMed Publications
IRF3 antibody	>12 publications with IFNb and IRF3
IFNAR1 antibody	>4 publications with IFNb and IFNAR1
IRF7 antibody	>3 publications with IFNb and IRF7
STAT2 antibody	>2 publications with IFNb and STAT2
EP300 antibody	>1 publications with IFNb and EP300
CREBBP antibody	>1 publications with IFNb and CREBBP
IRF1 antibody	>1 publications with IFNb and IRF1
IFNAR2 antibody	>1 publications with IFNb and IFNAR2

Pathways associated with anti-IFNb antibody

Products by Pathway	Pathway Diagram
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Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokines And Inflammatory Response Pathway antibodies	Cytokines And Inflammatory Response Pathway Diagram
Cytosolic DNA-sensing Pathway antibodies	Cytosolic DNA-sensing Pathway Diagram
Cytosolic DNA-sensing Pathway antibodies	Cytosolic DNA-sensing Pathway Diagram

Diseases associated with anti-IFNb antibody

Disease Name	Pubmed Publications
Necrosis Antibodies	>4 publications with IFNb and Necrosis
Inflammation Antibodies	>4 publications with IFNb and Inflammation
Carcinoma Antibodies	>4 publications with IFNb and Carcinoma
Lung Neoplasms Antibodies	>2 publications with IFNb and Lung Neoplasms
Multiple Sclerosis Antibodies	>2 publications with IFNb and Multiple Sclerosis
Melanoma Antibodies	>2 publications with IFNb and Melanoma
Cardiovascular Diseases Antibodies	>2 publications with IFNb and Cardiovascular Diseases
Brain Diseases Antibodies	>2 publications with IFNb and Brain Diseases
Neoplasms, Experimental Antibodies	>1 publications with IFNb and Neoplasms, Experimental
Pancreatic Neoplasms Antibodies	>1 publications with IFNb and Pancreatic Neoplasms