Mouse CXCL15 Active Protein – Cat# MBS695723

Lungkine (CXCL15) Mouse Active Protein

Name: CXCL15 Active Protein; Lungkine; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS695723
Price: 180 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS695723

Lungkine is a CXC chemokine that is expressed in lung epithelial cells and, to a lesser extent, in certain fetal tissues. No human homolog has been identified and a specific cell surface receptor has not yet been found. Lungkine expression in lung tissue is… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Lungkine (CXCL15), Active Protein

Full Product Name

Murine Lungkine (CXCL15)

Product Gene Name

CXCL15 active protein

Product Synonym Names

Recombinant Murine Lungkine (CXCL15)

Sequence

QELRCLCIQ EHSEFIPLK LIKNIMVIF ETIYCNRKE VIAVPKNGS MICLDPDAP WVKATVGPI TNRFLPEDL KQKEFPPAM KLLYSVEHE KPLYLSFGR PENKRIFPF PIRETSRHF ADLAHNSDR NFLRDSSEV SLTGSDA

Host

E Coli

Species Reactivity

Species Reactivity: Mouse
Cross Reactivity: Human

Form/Format

Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.

Purity/Purification

>=98% by SDS-PAGE gel and HPLC analyses.

Preparation and Storage

At -20°C

3D Structure

ModBase 3D Structure for Q9WVL7

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Authenticity

Verified by N-terminal and Mass Spectometry analyses (when applicable)

Biological Activity

Determined by its ability to chemoattract human neutrophils using a concentration range of 20.0-100.0 ng/ml.

Endotoxin

Endotoxin level is <0.1 ng/ug of protein (<1EU/ ug)

Protein content

Verified by UV Spectroscopy and /or SDS- PAGE gel

Reconstitution

Centrifuge the vial prior to opening . Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, It is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA)and store in working aliquots at -20°C or -80°C .

Product Categories/Family for CXCL15 active protein

Innate Immunity; Inflammation; Chemotaxis

Other Notes

Small volumes of CXCL15 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CXCL15 purchase

MBS695723 is an active protein targeting CXCL15. Also known as Murine Lungkine (CXCL15). Reactive in Species Reactivity: Mouse
Cross Reactivity: Human. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for CXCL15. It may not necessarily be applicable to this product.

NCBI GI #

7674364

NCBI GeneID

20309

NCBI Accession #

Q9WVL7.1

UniProt Primary Accession #

Q9WVL7

UniProt Secondary Accession #

Q3UQ15

UniProt Related Accession #

Q9WVL7

NCBI Official Full Name

C-X-C motif chemokine 15

NCBI Official Synonym Full Names

chemokine (C-X-C motif) ligand 15

NCBI Official Symbol

Cxcl15

NCBI Official Synonym Symbols

Il8; weche; Scyb15; lungkine

UniProt Protein Name

C-X-C motif chemokine 15

UniProt Synonym Protein Names

Lungkine; Small-inducible cytokine B15

Protein Family

C-X-C motif chemokine

UniProt Gene Name

Cxcl15

UniProt Synonym Gene Names

Scyb15

UniProt Entry Name

CXL15_MOUSE

NCBI Protein Information

C-X-C motif chemokine 15; interleukin 8; small-inducible cytokine B15; small inducible cytokine subfamily B, member 15

UniProt Comments for CXCL15

CXCL15: Chemotactic for neutrophils. May be involved in lung- specific neutrophil trafficking during normal and inflammatory conditions. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Chemokine

Cellular Component: extracellular space; extracellular region

Molecular Function: chemokine activity; CXCR chemokine receptor binding; cytokine activity

Biological Process: G-protein coupled receptor protein signaling pathway; neutrophil chemotaxis; positive regulation of leukocyte chemotaxis; hemopoiesis; response to lipopolysaccharide; immune response; inflammatory response; chemotaxis; regulation of cell proliferation

Research Articles on CXCL15

1. these data suggest that IL-8 plays an important role in breast cancer osteolysis

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CXCL15 active protein

Products by Pathway	Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram

Diseases associated with CXCL15 active protein

Disease Name	Pubmed Publications
Respiratory Tract Diseases Antibodies	>3 publications with CXCL15 and Respiratory Tract Diseases
Inflammation Antibodies	>3 publications with CXCL15 and Inflammation
Lung Diseases Antibodies	>2 publications with CXCL15 and Lung Diseases
Respiratory Hypersensitivity Antibodies	>1 publications with CXCL15 and Respiratory Hypersensitivity
Lung Neoplasms Antibodies	>1 publications with CXCL15 and Lung Neoplasms
Cardiovascular Diseases Antibodies	>1 publications with CXCL15 and Cardiovascular Diseases
Necrosis Antibodies	>1 publications with CXCL15 and Necrosis
Hypersensitivity Antibodies	>1 publications with CXCL15 and Hypersensitivity
Pneumonia Antibodies	>1 publications with CXCL15 and Pneumonia

Organs/Tissues associated with CXCL15 active protein

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>4 publications with CXCL15 and Lung