• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

IL-36RA Human Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS695883

The IL-1 family is comprised of 11 structurally related ligands, including the recently re-named IL-36RA (IL-1F5), IL-36 alpha (IL-1F6), IL-36beta (IL-1F8), and IL-36gamma (IL-1F9). The interaction of IL-36 ligands with the IL-1Rrp2 receptor (IL-1R6) can… More details

DISCONTINUED
Click here to view our similar product(s) OR click here to contact our technical support team for suitable replacement.
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Product Name
IL-36Ra, Active Protein
Full Product Name
Human IL-36Ra
Product Gene Name
Product Synonym Names
Recombinant Human IL-36RA
Sequence
VLSGALCFR MKDSALKVL YLHNNQLLA GGLHAEKVI KGEEISVVP NRALDASLS PVILGVQGG SQCLSCGTE KGPILKLEP VNIMELYLG AKESKSFTF YRRDMGLTS SFESAAYPG WFLCTSPEA DQPVRLTQI PEDPAWDAP ITDFYFQQC D
Host
E Coli
Species Reactivity
Species Reactivity: Human
Purity/Purification
Above 98% as determined by SDS-PAGE Analysis.
Preparation and Storage
At -20 degree C
Molecular Weight
17,136 Da
3D Structure
ModBase 3D Structure for Q9QYY1
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
Measured by its ability to inhibit IL-36gamma induced IL-6 production by human PBMCs.
Cell Type
Dendritic Cells

Testing Data of IL-36RA active protein

Human IL-36RA Active Protein – Cat# MBS695883

Other Notes

Small volumes of IL-36RA active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL-36RA purchase

MBS695883 is an active protein targeting IL-36RA. Also known as Human IL-36Ra. Reactive in Species Reactivity: Human. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-36RA. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Interleukin-36 receptor antagonist protein
NCBI Official Synonym Full Names
interleukin 1 family, member 5 (delta)
NCBI Official Symbol
Il1f5
NCBI Official Synonym Symbols
IL36RN; Il-1h3; Il1hy1; IL-36Ra; AI413231; Fil1delta
UniProt Protein Name
Interleukin-36 receptor antagonist protein
UniProt Synonym Protein Names
Interleukin-1 HY1; IL-1HY1; Interleukin-1 delta; IL-1 delta; Interleukin-1 family member 5; IL-1F5; Interleukin-1 homolog 3; IL-1H3; Interleukin-1-like protein 1; IL-1L1
UniProt Gene Name
IL36RN
UniProt Synonym Gene Names
Fil1d; Il1f5; Il1h3; Il1hy1; IL-1HY1; IL-1 delta; IL-1F5; IL-1H3; IL-1L1
UniProt Entry Name
I36RA_MOUSE
NCBI Protein Information
interleukin-36 receptor antagonist protein; IL-1F5; IL-1L1; IL-1HY1; IL-1 delta; interleukin-1 HY1; interleukin-1 delta; interleukin-1 homolog 3; interleukin-1-like protein 1; interleukin-1 family member 5; interleukin 1 receptor antagonist homolog 1

UniProt Comments for IL-36RA

Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2/IL-36R and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with IL-36RA active protein

Organs/Tissues associated with IL-36RA active protein

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000