Murine RETN Recombinant Protein – Cat# MBS695956

Resistin (RETN) Murine Recombinant Protein

Name: RETN Recombinant Protein; Resistin; Murine; MyBioSource
Brand: MyBioSource
SKU: MBS695956
Price: 180 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS695956

Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family; Resistin, RELM- alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Resistin (Retn), Recombinant Protein

Full Product Name

Murine Resistin

Product Gene Name

Retn recombinant protein

Product Synonym Names

Fizz3, Adipose tissue-specific secretory factor, ADSF

Sequence

SSMPLCPID EAIDKKIKQ DFNSLFPNA IKNIGLNCW TVSSRGKLA SCPEGTAVL SCSCGSACG SWDIREEKV CHCQCARID WTAARCCKL QVAS

Host

E Coli

Form/Format

Sterile filtered through a 0.2 micron filter. Lyophilized from 20 mM Tris, pH 8.0

Purity/Purification

>= 98% by SDS-PAGE gel and HPLC analysis.

Preparation and Storage

Store at -20 degree C.

3D Structure

ModBase 3D Structure for Q99P87

Authenticity

Verified by N-terminal and Mass Spectrometry analyses (when applicable).

Endotoxin

Endotoxin level is <0.1 ng/ug of protein (<1EU/ug)

Protein Content

Verified by UV Spectroscopy and/or SDS-PAGE gel.

Reconstituion

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containg a carrier protein (example 0.1 BSA) and store in working aliquots at -20°C to -80°C.

Product Categories/Family for Retn recombinant protein

Angiogenesis; Inflammation; Metabolic Regulation and Diabetes

Other Notes

Small volumes of Retn recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Retn purchase

MBS695956 is a recombinant protein targeting Retn. Also known as Murine Resistin. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for Retn. It may not necessarily be applicable to this product.

NCBI GI #

17380301

NCBI GeneID

57264

NCBI Accession #

Q99P87.1

UniProt Primary Accession #

Q99P87

UniProt Related Accession #

Q99P87

NCBI Official Full Name

Resistin

NCBI Official Synonym Full Names

resistin

NCBI Official Symbol

Retn

NCBI Official Synonym Symbols

ADSF; Rstn; Xcp4; Fizz3

UniProt Protein Name

Resistin

UniProt Synonym Protein Names

Adipose tissue-specific secretory factor; ADSF; Adipose-specific cysteine-rich secreted protein A12-alpha; Cysteine-rich secreted protein FIZZ3

Protein Family

Protein dead ringer

UniProt Gene Name

Retn

UniProt Synonym Gene Names

Fizz3; ADSF

UniProt Entry Name

RETN_MOUSE

NCBI Protein Information

resistin; found in inflammatory zone 3; cysteine-rich secreted protein FIZZ3; adipose tissue-specific secretory factor; dominant inhibitory adipocyte-specific secretory factor; adipose-specific cysteine-rich secreted protein A12-alpha

UniProt Comments for Retn

resistin: Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes. Belongs to the resistin/FIZZ family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular space; extracellular region; nucleus

Molecular Function: hormone activity

Biological Process: fat cell differentiation; positive regulation of smooth muscle cell proliferation; positive regulation of smooth muscle cell migration; positive regulation of synaptic transmission; response to insulin stimulus

Research Articles on Retn

1. Resistin regulates PAI-1 expression in 3T3-L1 adipocytes via Akt phosphorylation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Retn recombinant protein

Products by Pathway	Pathway Diagram
Adipogenesis Pathway antibodies	Adipogenesis Pathway Diagram

Diseases associated with Retn recombinant protein

Disease Name	Pubmed Publications
Insulin Resistance Antibodies	>333 publications with Retn and Insulin Resistance
Inflammation Antibodies	>114 publications with Retn and Inflammation
Cardiovascular Diseases Antibodies	>107 publications with Retn and Cardiovascular Diseases
Diabetes Mellitus, Type 2 Antibodies	>102 publications with Retn and Diabetes Mellitus, Type 2
Necrosis Antibodies	>100 publications with Retn and Necrosis
Atherosclerosis Antibodies	>58 publications with Retn and Atherosclerosis
Hypertension Antibodies	>35 publications with Retn and Hypertension
Metabolic Syndrome X Antibodies	>32 publications with Retn and Metabolic Syndrome X
Heart Diseases Antibodies	>30 publications with Retn and Heart Diseases
Coronary Disease Antibodies	>29 publications with Retn and Coronary Disease

Organs/Tissues associated with Retn recombinant protein

Organ/Tissue Name	Pubmed Publications
Heart Antibodies	>27 publications with Retn and Heart
Kidney Antibodies	>18 publications with Retn and Kidney
Pancreas Antibodies	>13 publications with Retn and Pancreas
Thyroid Antibodies	>10 publications with Retn and Thyroid
Intestine Antibodies	>10 publications with Retn and Intestine
Lung Antibodies	>9 publications with Retn and Lung
Embryonic Tissue Antibodies	>7 publications with Retn and Embryonic Tissue
Spleen Antibodies	>3 publications with Retn and Spleen
Prostate Antibodies	>2 publications with Retn and Prostate
Mammary Gland Antibodies	>2 publications with Retn and Mammary Gland