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Prolactin (PRL) Rat Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS696101

Prolactin is a neuroendocrine hormone secreted by the pituitary gland. Its primary function is to promote and maintain lactation during pregnancy and suckling. In addition, Prolactin plays an immune-regulatory role by stimulating the activities of ornithine… More details

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Product Overview

Product Name
Prolactin (Prl), Active Protein
Full Product Name
Rat Prolactin
Product Gene Name
Prl active protein
Product Synonym Names
Recombinant Rat Prolactin
Sequence
MLPVCSGGD CQTPLPELF DRVVMLSHY IHTLYTDMF IEFDKQYVQ DREFIAKAI NDCPTSSLA TPEDKEQAQ KVPPEVLLN LILSLVHSW NDPLFQLIT GLGGIHEAP DAIISRAKE IEEQNKRLL EGIEKIISQ AYPEAKGNE IYLVWSQLP SLQGVDEES KDLAFYNNI RCLRRDSHK VDNYLKFLR CQIVHKNNC
Host
E Coli
Species Reactivity
Species Reactivity: Rat
Purity/Purification
Above 98% as determined by SDS-PAGE Analysis.
Preparation and Storage
At -20 degree C
Molecular Weight
25,753 Da
3D Structure
ModBase 3D Structure for P01237
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
Determined by its ability to induce the proliferation of rat Nb2-11 cells in the concentration range of 0.1-1.0 ng/ml.

Product Categories/Family for Prl active protein

Stem Cell Research; Neurosciences; Proliferation and Cell Cycle

Testing Data of Prl active protein

Rat PRL Active Protein – Cat# MBS696101

Other Notes

Small volumes of Prl active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Prl purchase

MBS696101 is an active protein targeting Prl. Also known as Rat Prolactin. Reactive in Species Reactivity: Rat. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for Prl. It may not necessarily be applicable to this product.

NCBI GI #
130938
NCBI GeneID
24683
NCBI Accession #
P01237.1
UniProt Primary Accession #
P01237
UniProt Secondary Accession #
P70520
UniProt Related Accession #
P01237
NCBI Official Full Name
Prolactin
NCBI Official Synonym Full Names
prolactin
NCBI Official Symbol
Prl
NCBI Official Synonym Symbols
PRLB; Prol; PRLSD1; Prl1a1; RNPROL; RATPRLSD1
UniProt Protein Name
Prolactin
Protein Family
Prolactin
UniProt Gene Name
Prl
UniProt Synonym Gene Names
PRL
UniProt Entry Name
PRL_RAT
NCBI Protein Information
prolactin; prolactin family 1, subfamily a, member 1

NCBI Summary for Prl

induces lactation; may facilitate decidual growth and placentation; promotes prostate epithelial cell proliferation [RGD, Feb 2006]

UniProt Comments for Prl

prolactin: Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family.

Protein type: Secreted; Motility/polarity/chemotaxis; Cytokine; Secreted, signal peptide

Cellular Component: extracellular region; secretory granule

Molecular Function: prolactin receptor binding; hormone activity

Biological Process: response to drug; circadian rhythm; lactation; maternal behavior; regulation of multicellular organism growth; positive regulation of JAK-STAT cascade; response to lipopolysaccharide; response to organic cyclic substance; response to estradiol stimulus; cellular response to hormone stimulus; response to ethanol; regulation of JAK-STAT cascade; ovulation cycle; mammary gland development; positive regulation of cell proliferation; parturition; regulation of ossification; multicellular organismal response to stress; positive regulation of epithelial cell proliferation; response to nutrient; STAT protein nuclear translocation
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Research Articles on Prl

1. High Prolactin expression is associated with Streptozotocin diabetes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with Prl active protein

 Products by Pathway  Pathway Diagram
 Amyloids Pathway antibodies  Amyloids Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Growth Hormone Receptor Signaling Pathway antibodies  Growth Hormone Receptor Signaling Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram

Diseases associated with Prl active protein

 Disease Name  Pubmed Publications
 Pituitary Neoplasms Antibodies  >2013 publications with Prl and Pituitary Neoplasms
 Hyperprolactinemia Antibodies  >1515 publications with Prl and Hyperprolactinemia
 Adenoma Antibodies  >1480 publications with Prl and Adenoma
 Prolactinoma Antibodies  >673 publications with Prl and Prolactinoma
 Mental Disorders Antibodies  >601 publications with Prl and Mental Disorders
 Amenorrhea Antibodies  >427 publications with Prl and Amenorrhea
 Galactorrhea Antibodies  >316 publications with Prl and Galactorrhea
 Growth Hormone-Secreting Pituitary Adenoma Antibodies  >261 publications with Prl and Growth Hormone-Secreting Pituitary Adenoma
 Infertility, Female Antibodies  >233 publications with Prl and Infertility, Female
 Hypogonadism Antibodies  >205 publications with Prl and Hypogonadism

Organs/Tissues associated with Prl active protein

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5108 publications with Prl and Brain
 Pituitary Gland Antibodies  >3979 publications with Prl and Pituitary Gland
 Inner Ear Antibodies  >2 publications with Prl and Inner Ear
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