Epiregulin (EREG) ELISA Kit for Human

Name: Human EREG ELISA Kit; Epiregulin; MyBioSource
Brand: MyBioSource
SKU: MBS697374
Price: 630 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS697374

Epiregulin is an EGF-related growth factor that binds specifically to EGFR (ErbB1) and ErbB4, but not ErbB2 or ErbB3. It is expressed mainly in the placenta and peripheral blood leukocytes, as well as in certain carcinomas of the bladder, lung, kidney and… More details

$630 / 1 Kit +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Epiregulin (EREG), ELISA Kit

Full Product Name

Human Epiregulin Pre-Coated ELISA Kit

Product Gene Name

EREG elisa kit

Species Reactivity

Human

Assay Type

Solid Phase Sandwich ELISA: 96-Well Strip Plate

Detection Range

156pg/ml-10,000pg/ml

Sensitivity

<10pg/ml

Specificity

Natural and recombinant Human Epiregulin

Preparation and Storage

Store the unopened product at 2-8 degree C.

Molecular Weight

19,044 Da

OMIM

602061

3D Structure

ModBase 3D Structure for O14944

Components

Anti-Human Epiregulin Pre-coated 96-well strip microplate
Human Epiregulin Standard
Human Epiregulin Biotinylated antibody (100x)
Avidin-Biotin-Peroxidase Complex (100x)
Sample Diluent
Antibody Diluent
Avidin-Biotin-Peroxidase Diluent
Wash Buffer Concentrate (Powder for 1000mL)
Color Developing Reagent
Stop Solution
Plate Sealers

Interference

No detectable cross-reactivity with other relevant proteins

Other Notes

Small volumes of EREG elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EREG purchase

MBS697374 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Epiregulin (EREG) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing EREG. The ELISA analytical biochemical technique of the MBS697374 kit is based on EREG antibody-EREG antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect EREG antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, EREG. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for EREG. It may not necessarily be applicable to this product.

NCBI GI #

4557567

NCBI GeneID

2069

NCBI Accession #

NP_001423.1

UniProt Primary Accession #

O14944

UniProt Secondary Accession #

Q6FH69; B2RC66

UniProt Related Accession #

O14944

GenBank Nucleotide #

NM_001432.2

NCBI Official Full Name

proepiregulin preproprotein

NCBI Official Synonym Full Names

epiregulin

NCBI Official Symbol

EREG

NCBI Official Synonym Symbols

ER; Ep; EPR

UniProt Protein Name

Proepiregulin

Protein Family

Proepiregulin

UniProt Gene Name

EREG

UniProt Synonym Gene Names

EPR

UniProt Entry Name

EREG_HUMAN

NCBI Protein Information

proepiregulin

UniProt Comments for EREG

Epiregulin: Ligand of the EGF receptor/EGFR and ERBB4. May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: extracellular region; extracellular space; integral to plasma membrane

Molecular Function: epidermal growth factor receptor binding; growth factor activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein binding; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity

Biological Process: anatomical structure morphogenesis; cell-cell signaling; cytokine and chemokine mediated signaling pathway; epidermal growth factor receptor signaling pathway; female meiosis; keratinocyte differentiation; keratinocyte proliferation; luteinizing hormone signaling pathway; MAPKKK cascade; mRNA transcription; negative regulation of cell proliferation; negative regulation of epithelial cell proliferation; negative regulation of smooth muscle cell differentiation; negative regulation of transcription, DNA-dependent; oocyte maturation; organ morphogenesis; ovarian cumulus expansion; ovulation; phosphoinositide-mediated signaling; positive regulation of cell proliferation; positive regulation of cytokine biosynthetic process; positive regulation of cytokine production; positive regulation of DNA replication; positive regulation of epidermal growth factor receptor activity; positive regulation of fibroblast proliferation; positive regulation of innate immune response; positive regulation of interleukin-6 biosynthetic process; positive regulation of mitosis; positive regulation of phosphorylation; positive regulation of protein kinase activity; positive regulation of smooth muscle cell proliferation; primary follicle stage, oogenesis; regulation of phosphoinositide 3-kinase cascade; wound healing

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with EREG elisa kit

Reference Product	PubMed Publications
AREG elisa kit	>146 publications with EREG and AREG
EGFR elisa kit	>116 publications with EREG and EGFR
HBEGF elisa kit	>32 publications with EREG and HBEGF
ERBB2 elisa kit	>26 publications with EREG and ERBB2
ERBB4 elisa kit	>12 publications with EREG and ERBB4
ERBB3 elisa kit	>11 publications with EREG and ERBB3
NRG1 elisa kit	>9 publications with EREG and NRG1
NRG2 elisa kit	>6 publications with EREG and NRG2
NRG4 elisa kit	>3 publications with EREG and NRG4

Pathways associated with EREG elisa kit

Products by Pathway	Pathway Diagram
ARMS-mediated Activation Pathway antibodies	ARMS-mediated Activation Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Constitutive Signaling By Aberrant PI3K In Cancer Pathway antibodies	Constitutive Signaling By Aberrant PI3K In Cancer Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
DAP12 Interactions Pathway antibodies	DAP12 Interactions Pathway Diagram
DAP12 Signaling Pathway antibodies	DAP12 Signaling Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Diseases Of Signal Transduction Pathway antibodies	Diseases Of Signal Transduction Pathway Diagram

Diseases associated with EREG elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>19 publications with EREG and Inflammation
Adenocarcinoma Antibodies	>18 publications with EREG and Adenocarcinoma
Lung Neoplasms Antibodies	>16 publications with EREG and Lung Neoplasms
Breast Neoplasms Antibodies	>16 publications with EREG and Breast Neoplasms
Lung Diseases Antibodies	>15 publications with EREG and Lung Diseases
Necrosis Antibodies	>12 publications with EREG and Necrosis
Neoplasms, Experimental Antibodies	>8 publications with EREG and Neoplasms, Experimental
Cell Transformation, Neoplastic Antibodies	>7 publications with EREG and Cell Transformation, Neoplastic
Cardiovascular Diseases Antibodies	>7 publications with EREG and Cardiovascular Diseases
Liver Diseases Antibodies	>7 publications with EREG and Liver Diseases

Organs/Tissues associated with EREG elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>27 publications with EREG and Blood
Lung Antibodies	>26 publications with EREG and Lung
Skin Antibodies	>17 publications with EREG and Skin
Liver Antibodies	>14 publications with EREG and Liver
Muscle Antibodies	>13 publications with EREG and Muscle
Mouth Antibodies	>9 publications with EREG and Mouth
Intestine Antibodies	>7 publications with EREG and Intestine
Brain Antibodies	>5 publications with EREG and Brain
Kidney Antibodies	>4 publications with EREG and Kidney
Lymph Node Antibodies	>2 publications with EREG and Lymph Node