Murine MIP-3beta ELISA Kit – Cat# MBS697415

MIP-3beta (CCL19) (MIP-3beta) ELISA Kit for Murine

Name: Murine MIP-3beta ELISA Kit; MIP-3beta (CCL19); MyBioSource
Brand: MyBioSource
SKU: MBS697415
Price: 600 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS697415

MIP-3beta is a CC chemokine, expressed in the thymus, lymph nodes, and in activated bone marrow stromal cells that signals through the CCR7 receptor. MIP-3beta is a chemoattractant for T and B lymphocytes, and myeloid progenitor cells.Murine MIP-3beta (CCL19)… More details

$600 / 1 Kit +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

MIP-3beta (CCL19), ELISA Kit

Full Product Name

Murine MIP-3beta (CCL19) Pre-Coated ELISA Kit

Product Gene Name

MIP-3beta elisa kit

Species Reactivity

Murine

Assay Type

Solid Phase Sandwich ELISA: 96-Well Strip Plate

Detection Range

15.6pg/ml-1000pg/ml

Sensitivity

<10pg/ml

Specificity

Natural and recombinant Murine MIP-3beta (CCL19)

Preparation and Storage

Store the unopened product at 2-8 degree C.

Molecular Weight

11,911 Da

3D Structure

ModBase 3D Structure for O70460

Components

Anti-Murine MIP-3beta (CCL19) Pre-coated 96-well strip microplate
Murine MIP-3beta (CCL19) Standard
Murine MIP-3beta (CCL19) Biotinylated antibody (100x)
Avidin-Biotin-Peroxidase Complex (100x)
Sample Diluent
Antibody Diluent
Avidin-Biotin-Peroxidase Diluent
Wash Buffer Concentrate (Powder for 1000mL)
Color Developing Reagent
Stop Solution
Plate Sealers

Interference

No detectable cross-reactivity with other relevant proteins

Other Notes

Small volumes of MIP-3beta elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MIP-3beta purchase

MBS697415 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the MIP-3beta (CCL19) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MIP-3beta. The ELISA analytical biochemical technique of the MBS697415 kit is based on MIP-3beta antibody-MIP-3beta antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MIP-3beta antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MIP-3beta. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for MIP-3beta. It may not necessarily be applicable to this product.

NCBI GI #

6755422

NCBI GeneID

24047

NCBI Accession #

NP_036018.1

UniProt Primary Accession #

O70460

UniProt Related Accession #

O70460

GenBank Nucleotide #

NM_011888.2

NCBI Official Full Name

C-C motif chemokine 19

NCBI Official Synonym Full Names

chemokine (C-C motif) ligand 19

NCBI Official Symbol

Ccl19

NCBI Official Synonym Symbols

ELC; CKb11; MIP3B; Scya19; exodus-3

UniProt Protein Name

C-C motif chemokine 19

UniProt Synonym Protein Names

Epstein-Barr virus-induced molecule 1 ligand chemokine; EBI1 ligand chemokine; ELC; Small-inducible cytokine A19

UniProt Gene Name

Ccl19

UniProt Synonym Gene Names

Elc; Scya19; EBI1 ligand chemokine; ELC

UniProt Entry Name

CCL19_MOUSE

NCBI Protein Information

C-C motif chemokine 19; EBI-1 ligand chemokine; EBI1 ligand chemokine; EBI1-ligand chemokine; EBV-induced molecule 1 ligand chemokine; chemokine CCL19; epstein-Barr virus-induced molecule 1 ligand chemokine; small inducible cytokine A19; small-inducible c

UniProt Comments for MIP-3beta

CCL19: May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Specifically binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide

Cellular Component: cell; intracellular; cytosol; external side of plasma membrane

Molecular Function: CCR chemokine receptor binding; chemokine activity; chemokine receptor binding; CCR10 chemokine receptor binding

Biological Process: positive regulation of protein kinase B signaling cascade; myeloid dendritic cell chemotaxis; positive regulation of I-kappaB kinase/NF-kappaB cascade; release of sequestered calcium ion into cytosol; positive regulation of protein kinase activity; positive regulation of JNK cascade; dendritic cell chemotaxis; positive regulation of phosphoinositide 3-kinase activity; establishment of T cell polarity; positive regulation of NF-kappaB import into nucleus

Research Articles on MIP-3beta

1. CCL19 (ELC) improves TH1-polarized immune responses and protective immunity in a murine Her2/neu DNA vaccination model.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with MIP-3beta elisa kit

Reference Product	PubMed Publications
Ccr7 elisa kit	>446 publications with MIP-3beta and Ccr7
Cxcl12 elisa kit	>135 publications with MIP-3beta and Cxcl12
Cxcl13 elisa kit	>99 publications with MIP-3beta and Cxcl13
Ccr6 elisa kit	>47 publications with MIP-3beta and Ccr6
Cxcl9 elisa kit	>37 publications with MIP-3beta and Cxcl9
Ccl17 elisa kit	>31 publications with MIP-3beta and Ccl17
Cxcr5 elisa kit	>31 publications with MIP-3beta and Cxcr5
Ccl25 elisa kit	>30 publications with MIP-3beta and Ccl25
Cxcr3 elisa kit	>27 publications with MIP-3beta and Cxcr3

Pathways associated with MIP-3beta elisa kit

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies	Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram

Diseases associated with MIP-3beta elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>152 publications with MIP-3beta and Inflammation
Necrosis Antibodies	>66 publications with MIP-3beta and Necrosis
Lung Diseases Antibodies	>44 publications with MIP-3beta and Lung Diseases
Vascular Diseases Antibodies	>34 publications with MIP-3beta and Vascular Diseases
Hypersensitivity Antibodies	>28 publications with MIP-3beta and Hypersensitivity
Death Antibodies	>21 publications with MIP-3beta and Death
Lung Neoplasms Antibodies	>14 publications with MIP-3beta and Lung Neoplasms
Respiratory Tract Infections Antibodies	>14 publications with MIP-3beta and Respiratory Tract Infections
Liver Diseases Antibodies	>13 publications with MIP-3beta and Liver Diseases
Heart Diseases Antibodies	>12 publications with MIP-3beta and Heart Diseases

Organs/Tissues associated with MIP-3beta elisa kit

Organ/Tissue Name	Pubmed Publications
Lymph Node Antibodies	>283 publications with MIP-3beta and Lymph Node
Spleen Antibodies	>71 publications with MIP-3beta and Spleen
Thymus Antibodies	>38 publications with MIP-3beta and Thymus
Embryonic Tissue Antibodies	>13 publications with MIP-3beta and Embryonic Tissue
Salivary Gland Antibodies	>7 publications with MIP-3beta and Salivary Gland
Mammary Gland Antibodies	>1 publications with MIP-3beta and Mammary Gland