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Elastin Microfibril Interface Located Protein 1 (EMILIN1) Homo Sapiens (Human) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS2031693
SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment

MBS2031693 is a recombinant protein targeting EMILIN1. Also known as Recombinant Elastin Microfibril Interface Located Protein 1 (EMILIN1). Reactive in Homo sapiens (Human). Host: E.coli. More details

$215 / 0.01 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Elastin Microfibril Interface Located Protein 1 (EMILIN1), Recombinant Protein
Full Product Name
Recombinant Elastin Microfibril Interface Located Protein 1 (EMILIN1)
Product Gene Name
EMILIN1 recombinant protein
Host
E.coli
Species Reactivity
Homo sapiens (Human)
Form/Format
PBS, pH7.4, containing 0.01% Sarcosyl, 5% Trehalose.
Purity/Purification
> 90%
Concentration
Original Concentration: 300ug/mL (lot specific)
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 2-8 degree C for one month.
Aliquot and store at -80 degree C for 12 months.

Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Matching Pairs
Unconjugated Antibody: EMILIN1 (MBS2026449)
Immunogen: EMILIN1 (MBS2031693)
Matching Pairs
APC-CY7 Conjugated Antibody: EMILIN1 (MBS2042139)
Immunogen: EMILIN1 (MBS2031693)
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Molecular Weight
Predicted Molecular Mass: 28.8kDa
Accurate Molecular Mass: 31kDa as determined by SDS-PAGE reducing conditions.
OMIM
130660
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Source
Prokaryotic expression
Residues
Gln806~Ala1016
Tags
N-terminal His Tag
Subcellular Location
Secreted, Extracellular matrix
Traits
Freeze-dried powder
Predicted isoelectric point
5.1
Usage
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
ISO Certification
Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
Applications Tested/Suitable for EMILIN1 recombinant protein
Positive Control; Immunogen; SDS-PAGE; Western Blot (WB)
Application Notes for EMILIN1 recombinant protein
(May be suitable for use in other assays to be determined by the end user.)

Sequence of EMILIN1 recombinant protein

Homo Sapiens (Human) EMILIN1 Recombinant Protein – Cat# MBS2031693

SDS-Page of EMILIN1 recombinant protein

Homo Sapiens (Human) EMILIN1 Recombinant Protein, SDS-Page – Cat# MBS2031693

Other Notes

Small volumes of EMILIN1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EMILIN1. It may not necessarily be applicable to this product.

NCBI GI #
5901944
NCBI GeneID
11117
NCBI Accession #
NP_008977.1
UniProt Secondary Accession #
Q53SY9; Q96G58; Q96IH6; Q9UG76; A5PL03; H0Y7A0
UniProt Related Accession #
Q9Y6C2
GenBank Nucleotide #
NM_007046.3
NCBI Official Full Name
EMILIN-1
NCBI Official Synonym Full Names
elastin microfibril interfacer 1
NCBI Official Symbol
EMILIN1
NCBI Official Synonym Symbols
EMI; gp115; EMILIN
UniProt Protein Name
EMILIN-1
UniProt Synonym Protein Names
Elastin microfibril interface-located protein 1; Elastin microfibril interfacer 1
Protein Family
EMILIN
UniProt Gene Name
EMILIN1
UniProt Synonym Gene Names
EMI; Elastin microfibril interfacer 1
UniProt Entry Name
EMIL1_HUMAN
NCBI Protein Information
EMILIN-1

NCBI Summary for EMILIN1

This gene encodes an extracellular matrix glycoprotein that is characterized by an N-terminal microfibril interface domain, a coiled-coiled alpha-helical domain, a collagenous domain and a C-terminal globular C1q domain. The encoded protein associates with elastic fibers at the interface between elastin and microfibrils and may play a role in the development of elastic tissues including large blood vessels, dermis, heart and lung. [provided by RefSeq, Sep 2009]
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UniProt Comments for EMILIN1

EMILIN1: May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide; Cell adhesion; Extracellular matrix

Chromosomal Location of Human Ortholog: 2p23.3-p23.2

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; collagen; extracellular region

Molecular Function: identical protein binding; protein binding; extracellular matrix constituent conferring elasticity

Biological Process: extracellular matrix organization and biogenesis; cell adhesion
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Research Articles on EMILIN1

1. The present findings highlight the peculiar activity of PMN elastase in disabling EMILIN1 suppressor function.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with EMILIN1 recombinant protein

 Reference Product  PubMed Publications
 EMILIN2 recombinant protein  >7 publications with EMILIN1 and EMILIN2

Diseases associated with EMILIN1 recombinant protein

 Disease Name  Pubmed Publications
 Hypertension Antibodies  >10 publications with EMILIN1 and Hypertension
 Death Antibodies  >3 publications with EMILIN1 and Death
 Lung Diseases Antibodies  >1 publications with EMILIN1 and Lung Diseases
 Neoplasm Metastasis Antibodies  >1 publications with EMILIN1 and Neoplasm Metastasis
 Cardiovascular Abnormalities Antibodies  >1 publications with EMILIN1 and Cardiovascular Abnormalities
 Heart Defects, Congenital Antibodies  >1 publications with EMILIN1 and Heart Defects, Congenital
 Congenital Abnormalities Antibodies  >1 publications with EMILIN1 and Congenital Abnormalities
 Fibrosis Antibodies  >1 publications with EMILIN1 and Fibrosis
 Hyperplasia Antibodies  >1 publications with EMILIN1 and Hyperplasia
 Inflammation Antibodies  >1 publications with EMILIN1 and Inflammation

Organs/Tissues associated with EMILIN1 recombinant protein

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >3 publications with EMILIN1 and Skin
 Heart Antibodies  >3 publications with EMILIN1 and Heart
 Connective Tissue Antibodies  >2 publications with EMILIN1 and Connective Tissue
 Uterus Antibodies  >2 publications with EMILIN1 and Uterus
 Placenta Antibodies  >2 publications with EMILIN1 and Placenta
 Embryonic Tissue Antibodies  >2 publications with EMILIN1 and Embryonic Tissue
 Kidney Antibodies  >1 publications with EMILIN1 and Kidney
 Bone Antibodies  >1 publications with EMILIN1 and Bone
 Lung Antibodies  >1 publications with EMILIN1 and Lung
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