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GABPB1 Human Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS698087

MBS698087 is a recombinant protein targeting GABPB1. Also known as Human GABPB1 Recombinant Protein. Host: E Coli. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
GABPB1, Recombinant Protein
Full Product Name
Human GABPB1 Recombinant Protein
Product Synonym Names
GA-Binding Protein Subunit beta-1; E4TF1; GABPB; BABPB2; E4TF1B; GABPB2; NRF2B1; NRF2B2; GABPB-1; E4TF1-47; E4TF1-52
Host
E Coli
Form/Format
Frozen/Solution; 20mM Tris pH 8, 0.5M NaCl, 500 mM Imidazole
Purity/Purification
>90%
Purification: 6xHis tag, Immobilized-metal affinity chromatography (IMAC)
Preparation and Storage
For extended storage, conserve at -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Molecular Weight
43305.52
Sequence Positions
1-395 (Full Length)
OMIM
600610
3D Structure
ModBase 3D Structure for Q06547
Organism Species
Human
Biological Activity
Not tested
Endotoxin Level
Not tested
Quality Control
10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-6xHis monoclonal and peptide fingerprinting by MALDI-TOF mass spectrometry
Applications Tested/Suitable for GABPB1 recombinant protein
ELISA (EIA), Western Blot (WB), Antibody Production, Protein Array

Other Notes

Small volumes of GABPB1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for GABPB1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
GA-binding protein subunit beta-1 isoform beta 1
NCBI Official Synonym Full Names
GA binding protein transcription factor subunit beta 1
NCBI Official Symbol
GABPB1
NCBI Official Synonym Symbols
E4TF1; GABPB; BABPB2; E4TF1B; GABPB2; NRF2B1; NRF2B2; GABPB-1; E4TF1-47; E4TF1-53
UniProt Protein Name
GA-binding protein subunit beta-1
UniProt Synonym Protein Names
GABP subunit beta-2; GABPB-2; Nuclear respiratory factor 2; Transcription factor E4TF1-47; Transcription factor E4TF1-53
Protein Family
UniProt Gene Name
GABPB1
UniProt Synonym Gene Names
E4TF1B; GABPB; GABPB2; GABP subunit beta-1; GABPB-1; GABPB-2
UniProt Entry Name
GABP1_HUMAN
NCBI Protein Information
GA-binding protein subunit beta-1

NCBI Summary for GABPB1

This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for GABPB1

GABPB1: Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 15q21.2

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; protein heterodimerization activity; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; mitochondrion organization and biogenesis; transcription, DNA-dependent; organelle organization and biogenesis; positive regulation of transcription from RNA polymerase II promoter
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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