Human FLT3LG Recombinant Protein – Cat# MBS698091

FLT3LG Human Recombinant Protein

Name: FLT3LG Recombinant Protein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS698091
Price: 630 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS698091

MBS698091 is a recombinant protein targeting FLT3LG. Also known as Human FLT3LG Recombinant Protein. Host: Sf9-Baculovirus. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

FLT3LG, Recombinant Protein

Full Product Name

Human FLT3LG Recombinant Protein

Product Gene Name

FLT3LG recombinant protein

Product Synonym Names

Fms Related Tyrosine Kinase 3 Ligand; FL; FLT3L

Host

Sf9-Baculovirus

Form/Format

Frozen/Solution; PBS and 10mM Reduced Glutation

Purity/Purification

>70%
Purification: GST tag, affinity chromatography

Preparation and Storage

For extended storage, conserve at -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.

Molecular Weight

51092.34

Sequence Positions

26-234 (Without Signal Peptide)

OMIM

600007

3D Structure

ModBase 3D Structure for P49771

Organism Species

Human

Biological Activity

Not tested

Endotoxin Level

Not tested

Quality Control

10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-GST monoclonal and peptide fingerprinting by MALDI-TOF mass spectrometry

Product Categories/Family for FLT3LG recombinant protein

Ligand; Signal Transduction

Applications Tested/Suitable for FLT3LG recombinant protein

ELISA (EIA), Western Blot (WB), Antibody Production, Protein Array

Other Notes

Small volumes of FLT3LG recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FLT3LG. It may not necessarily be applicable to this product.

NCBI GI #

38455416

NCBI GeneID

2323

NCBI Accession #

NP_001450

UniProt Primary Accession #

P49771

UniProt Related Accession #

P49771

GenBank Nucleotide #

NM_001459.3

NCBI Official Full Name

fms-related tyrosine kinase 3 ligand isoform 1

NCBI Official Synonym Full Names

fms related receptor tyrosine kinase 3 ligand

NCBI Official Symbol

FLT3LG

NCBI Official Synonym Symbols

FL; FLG3L; FLT3L

UniProt Protein Name

Fms-related tyrosine kinase 3 ligand

UniProt Synonym Protein Names

SL cytokine

Protein Family

Fms-related tyrosine kinase

UniProt Gene Name

FLT3LG

UniProt Synonym Gene Names

Flt3 ligand; Flt3L

UniProt Entry Name

FLT3L_HUMAN

NCBI Protein Information

fms-related tyrosine kinase 3 ligand

NCBI Summary for FLT3LG

Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]

UniProt Comments for FLT3LG

FLT3LG: Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine; Ligand, receptor tyrosine kinase; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: extracellular space; membrane; integral to membrane

Molecular Function: protein homodimerization activity; cytokine activity; receptor tyrosine kinase binding; receptor binding

Biological Process: positive regulation of natural killer cell differentiation; regulation of myeloid dendritic cell activation; lymphocyte differentiation; embryonic hemopoiesis; positive regulation of cell proliferation; positive regulation of protein amino acid phosphorylation; signal transduction; positive regulation of myoblast differentiation

Research Articles on FLT3LG

1. the sFLc kinetic profile during induction appears to be a powerful early prognostic marker to take into account as it may help to classify AML patients better

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with FLT3LG recombinant protein

Products by Pathway	Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Pathways In Cancer antibodies	Pathways In Cancer Diagram
Signaling By Interleukins Pathway antibodies	Signaling By Interleukins Pathway Diagram

Diseases associated with FLT3LG recombinant protein

Disease Name	Pubmed Publications
Leukemia Antibodies	>2 publications with FLT3LG and Leukemia
Chromosome Aberrations Antibodies	>1 publications with FLT3LG and Chromosome Aberrations
Cell Transformation, Neoplastic Antibodies	>1 publications with FLT3LG and Cell Transformation, Neoplastic
Inflammation Antibodies	>1 publications with FLT3LG and Inflammation

Organs/Tissues associated with FLT3LG recombinant protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>5 publications with FLT3LG and Blood
Pancreas Antibodies	>1 publications with FLT3LG and Pancreas