Chicken IL-12/70 ELISA Kit – Cat# MBS700437

Interleukin 12, Il-12/70 (IL-12/70) ELISA Kit for Chicken

Name: Chicken IL-12/70 ELISA Kit; Interleukin 12, Il-12/70; MyBioSource
Brand: MyBioSource
SKU: MBS700437
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS700437

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to IL-12/70. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

Interleukin 12, IL-12/70, ELISA Kit

Full Product Name

Chicken Interleukin 12, IL-12/70 ELISA Kit

Product Gene Name

IL-12/70 elisa kit

Product Synonym Names

Chicken Interleukin 12; IL-12/70 ELISA Kit; Interleukin 12; IL-12/70

Species Reactivity

Chicken

Samples

Serum, plasma and tissue homogenates

Detection Range

0.78 pg/ml-200 pg/ml

Sensitivity

0.78 pg/ml

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Molecular Weight

24,874 Da

OMIM

161560

3D Structure

ModBase 3D Structure for P29459

Detection Wavelength

450 nm

Sample Volume

50-100ul

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of IL-12/70 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL-12/70 purchase

MBS700437 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Interleukin 12, IL-12/70, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IL-12/70. The ELISA analytical biochemical technique of the MBS700437 kit is based on IL-12/70 antibody-IL-12/70 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL-12/70 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL-12/70. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for IL-12/70. It may not necessarily be applicable to this product.

NCBI GI #

4323579

NCBI GeneID

3592

NCBI Accession #

AAD16432.1

UniProt Primary Accession #

P29459

UniProt Secondary Accession #

Q96QZ1

UniProt Related Accession #

P29459

NCBI Official Full Name

interleukin 12

NCBI Official Synonym Full Names

interleukin 12A

NCBI Official Symbol

IL12A

NCBI Official Synonym Symbols

P35; CLMF; NFSK; NKSF1; IL-12A

UniProt Protein Name

Interleukin-12 subunit alpha

UniProt Synonym Protein Names

Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; NK cell stimulatory factor chain 1; NKSF1

UniProt Gene Name

IL12A

UniProt Synonym Gene Names

NKSF1; IL-12A; CLMF p35; NKSF1

UniProt Entry Name

IL12A_HUMAN

NCBI Protein Information

interleukin-12 subunit alpha; CLMF p35; IL35 subunit; IL-12, subunit p35; interleukin 12, p35; interleukin-12 alpha chain; NF cell stimulatory factor chain 1; NK cell stimulatory factor chain 1; cytotoxic lymphocyte maturation factor 1, p35; cytotoxic lymphocyte maturation factor 35 kDa subunit; interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

NCBI Summary for IL-12/70

This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]

UniProt Comments for IL-12/70

Function: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.

Research Articles on IL-12/70

1. circulating IL-35 in PDAC patients significantly increased, suggesting that regulating the expression of IL-35 may provide a new possible target for the treatment of PDAC patients, especially for the resectable ones.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IL-12/70 elisa kit

Reference Product	PubMed Publications
IL12B elisa kit	>47 publications with IL-12/70 and IL12B
IL4 elisa kit	>18 publications with IL-12/70 and IL4
IFNG elisa kit	>15 publications with IL-12/70 and IFNG
IL12RB2 elisa kit	>12 publications with IL-12/70 and IL12RB2
IL1B elisa kit	>11 publications with IL-12/70 and IL1B
IL12RB1 elisa kit	>10 publications with IL-12/70 and IL12RB1
STAT1 elisa kit	>5 publications with IL-12/70 and STAT1
JAK2 elisa kit	>1 publications with IL-12/70 and JAK2

Pathways associated with IL-12/70 elisa kit

Products by Pathway	Pathway Diagram
African Trypanosomiasis Pathway antibodies	African Trypanosomiasis Pathway Diagram
African Trypanosomiasis Pathway antibodies	African Trypanosomiasis Pathway Diagram
Allograft Rejection Pathway antibodies	Allograft Rejection Pathway Diagram
Allograft Rejection Pathway antibodies	Allograft Rejection Pathway Diagram
Allograft Rejection Pathway antibodies	Allograft Rejection Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Amoebiasis Pathway antibodies	Amoebiasis Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram

Diseases associated with IL-12/70 elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>18 publications with IL-12/70 and Inflammation
Necrosis Antibodies	>16 publications with IL-12/70 and Necrosis
Liver Diseases Antibodies	>11 publications with IL-12/70 and Liver Diseases
Disease Models, Animal Antibodies	>10 publications with IL-12/70 and Disease Models, Animal
Multiple Sclerosis Antibodies	>10 publications with IL-12/70 and Multiple Sclerosis
Hepatitis Antibodies	>7 publications with IL-12/70 and Hepatitis
Brain Diseases Antibodies	>7 publications with IL-12/70 and Brain Diseases
Liver Cirrhosis, Biliary Antibodies	>7 publications with IL-12/70 and Liver Cirrhosis, Biliary
Neoplasms, Experimental Antibodies	>5 publications with IL-12/70 and Neoplasms, Experimental
Cell Transformation, Neoplastic Antibodies	>4 publications with IL-12/70 and Cell Transformation, Neoplastic

Organs/Tissues associated with IL-12/70 elisa kit

Organ/Tissue Name	Pubmed Publications
Spleen Antibodies	>4 publications with IL-12/70 and Spleen
Uterus Antibodies	>2 publications with IL-12/70 and Uterus
Brain Antibodies	>2 publications with IL-12/70 and Brain