Paraoxonase 1 (PON1) ELISA Kit for Rat

Name: Rat PON1 ELISA Kit; Paraoxonase 1; MyBioSource
Brand: MyBioSource
SKU: MBS700534
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS700534

MBS700534 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the paraoxonase 1 (PON1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

paraoxonase 1 (PON1), ELISA Kit

Full Product Name

Rat Paraoxonase 1, PON1 ELISA Kit

Product Gene Name

PON1 elisa kit

Product Synonym Names

Rat Paraoxonase 1 (PON1) ELISA Kit; ESA; MVCD5; PON; arylesterase B-type; esterase A; paraoxonase B-type; serum aryldiakylphosphatase; paraoxonase 1

Species Reactivity

Rat

Assay Type

Sandwich (Quantitative)

Samples

serum, plasma, tissue homogenates.

Detection Range

15.6 uU/ml -1000 uU/ml.

Sensitivity

Typically less than 3.9 uU/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of rat PON1. No significant cross-reactivity or interference between rat PON1 and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Inter-assay Precision

Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.

Molecular Weight

40,010 Da

3D Structure

ModBase 3D Structure for P27170

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PON1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PON1. It may not necessarily be applicable to this product.

NCBI GI #

126722853

NCBI GeneID

100009133

NCBI Accession #

NP_001075766.1

UniProt Primary Accession #

P27170

UniProt Secondary Accession #

Q9BGN1; Q9BGN2; Q9BGN3

UniProt Related Accession #

P27170

GenBank Nucleotide #

NM_001082297.1

NCBI Official Full Name

serum paraoxonase/arylesterase 1

NCBI Official Symbol

PON1

NCBI Official Synonym Symbols

PON

UniProt Protein Name

Serum paraoxonase/arylesterase 1

UniProt Synonym Protein Names

Aromatic esterase 1; A-esterase 1; Serum aryldialkylphosphatase 1

Protein Family

Serum paraoxonase/arylesterase

UniProt Gene Name

PON1

UniProt Synonym Gene Names

PON; PON 1; A-esterase 1

UniProt Entry Name

PON1_RABIT

NCBI Protein Information

serum paraoxonase/arylesterase 1; PON 1; A-esterase 1; aromatic esterase 1; serum aryldialkylphosphatase 1

UniProt Comments for PON1

Function: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification.1 PublicationManual assertion based on experiment in:Ref.3

Catalytic activity: A phenyl acetate + H2O = a phenol + acetate.1 PublicationManual assertion based on experiment in:Ref.4

Cofactor: Binds 2 calcium ions per subunit

Research Articles on PON1

1. ApoE mimetic peptide reduces plasma lipid hydroperoxide content with a concomitant increase in HDL paraoxonase activity

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PON1 elisa kit

Reference Product	PubMed Publications
APOE elisa kit	>77 publications with PON1 and APOE
APOA1 elisa kit	>31 publications with PON1 and APOA1
LCAT elisa kit	>26 publications with PON1 and LCAT
APOC3 elisa kit	>5 publications with PON1 and APOC3
LIPC elisa kit	>4 publications with PON1 and LIPC
APOA5 elisa kit	>4 publications with PON1 and APOA5
APOA2 elisa kit	>2 publications with PON1 and APOA2

Pathways associated with PON1 elisa kit

Products by Pathway	Pathway Diagram
Focal Adhesion Pathway antibodies	Focal Adhesion Pathway Diagram
Focal Adhesion Pathway antibodies	Focal Adhesion Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
MAPK Signaling Pathway antibodies	MAPK Signaling Pathway Diagram
Salmonella Infection Pathway antibodies	Salmonella Infection Pathway Diagram
Salmonella Infection Pathway antibodies	Salmonella Infection Pathway Diagram

Diseases associated with PON1 elisa kit

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>627 publications with PON1 and Cardiovascular Diseases
Atherosclerosis Antibodies	>487 publications with PON1 and Atherosclerosis
Coronary Disease Antibodies	>279 publications with PON1 and Coronary Disease
Diabetes Mellitus Antibodies	>163 publications with PON1 and Diabetes Mellitus
Coronary Artery Disease Antibodies	>161 publications with PON1 and Coronary Artery Disease
Inflammation Antibodies	>144 publications with PON1 and Inflammation
Kidney Diseases Antibodies	>83 publications with PON1 and Kidney Diseases
Poisoning Antibodies	>82 publications with PON1 and Poisoning
Organophosphate Poisoning Antibodies	>47 publications with PON1 and Organophosphate Poisoning
Hypercholesterolemia Antibodies	>44 publications with PON1 and Hypercholesterolemia

Organs/Tissues associated with PON1 elisa kit

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>13 publications with PON1 and Bone
Connective Tissue Antibodies	>4 publications with PON1 and Connective Tissue
Heart Antibodies	>3 publications with PON1 and Heart
Muscle Antibodies	>3 publications with PON1 and Muscle
Brain Antibodies	>3 publications with PON1 and Brain
Vascular Antibodies	>2 publications with PON1 and Vascular
Embryonic Tissue Antibodies	>2 publications with PON1 and Embryonic Tissue
Ear Antibodies	>1 publications with PON1 and Ear
Kidney Antibodies	>1 publications with PON1 and Kidney
Umbilical Cord Antibodies	>1 publications with PON1 and Umbilical Cord