Leptin Receptor (LEPR) ELISA Kit for Mouse

Name: Mouse LEPR ELISA Kit; Leptin Receptor; MyBioSource
Brand: MyBioSource
SKU: MBS700706
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS700706

MBS700706 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the leptin receptor (LEPR) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

leptin receptor (LEPR), ELISA Kit

Full Product Name

Mouse Leptin receptor, LR/Ob-R ELISA Kit

Product Gene Name

LEPR elisa kit

Product Synonym Names

Mouse Leptin receptor; LR/Ob-R ELISA KIT; CD295; OBR; OB receptor; OTTHUMP00000010694; leptin receptor

Species Reactivity

Mouse

Samples

Serum, plasma and tissue homogenates

Detection Range

15.62pg/ml-1000 pg/ml

Sensitivity

15.62pg/ml

Specificity

This assay has high sensitivity and excellent specificity for detection of Mouse LEPR. No significant cross-reactivity or interference between Mouse LEPR and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.

Molecular Weight

130,789 Da

3D Structure

ModBase 3D Structure for P48356

Detection Wavelength

450 nm

Sample Volume

50-100ul

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of LEPR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LEPR. It may not necessarily be applicable to this product.

NCBI GI #

171543892

NCBI GeneID

16847

NCBI Accession #

NP_001116371.1

UniProt Primary Accession #

P48356

UniProt Secondary Accession #

O35686; O54986; Q61215; Q64309; Q9QWG3; Q9QWV5

UniProt Related Accession #

P48356

GenBank Nucleotide #

NM_001122899.1

NCBI Official Full Name

leptin receptor isoform 3

NCBI Official Synonym Full Names

leptin receptor

NCBI Official Symbol

Lepr

NCBI Official Synonym Symbols

db; Obr; obl; Leprb; Modb1; LEPROT; OB-RGRP; diabetes; obese-like

UniProt Protein Name

Leptin receptor

UniProt Synonym Protein Names

B219; OB receptor; OB-R; CD_antigen: CD295

Protein Family

Leptin receptor

UniProt Gene Name

Lepr

UniProt Synonym Gene Names

Db; Obr; LEP-R; OB-R

UniProt Entry Name

LEPR_MOUSE

NCBI Protein Information

leptin receptor; B219; LEP-R; OB receptor; leptin receptor gene-related protein

UniProt Comments for LEPR

Function: Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway.

Research Articles on LEPR

1. results demonstrate that leptin receptor is dramatically induced in the granulosa cells of ovulating follicles and this induction of Lepr expression requires the transcription factor CCAAT/enhancer-binding protein beta

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with LEPR elisa kit

Reference Product	PubMed Publications
FLNA elisa kit	>12 publications with LEPR and FLNA

Pathways associated with LEPR elisa kit

Products by Pathway	Pathway Diagram
AMPK Signaling Pathway antibodies	AMPK Signaling Pathway Diagram
AMPK Signaling Pathway antibodies	AMPK Signaling Pathway Diagram
Adipocytokine Signaling Pathway antibodies	Adipocytokine Signaling Pathway Diagram
Adipocytokine Signaling Pathway antibodies	Adipocytokine Signaling Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram
Leptin Insulin Overlap Pathway antibodies	Leptin Insulin Overlap Pathway Diagram
Leptin And Adiponectin Pathway antibodies	Leptin And Adiponectin Pathway Diagram

Diseases associated with LEPR elisa kit

Disease Name	Pubmed Publications
Peripheral Nervous System Diseases Antibodies	>401 publications with LEPR and Peripheral Nervous System Diseases
Obesity Antibodies	>373 publications with LEPR and Obesity
Drug-Related Side Effects and Adverse Reactions Antibodies	>349 publications with LEPR and Drug-Related Side Effects and Adverse Reactions
Overweight Antibodies	>239 publications with LEPR and Overweight
Diabetes Mellitus Antibodies	>209 publications with LEPR and Diabetes Mellitus
Inflammation Antibodies	>198 publications with LEPR and Inflammation
Diabetes Mellitus, Type 2 Antibodies	>119 publications with LEPR and Diabetes Mellitus, Type 2
Insulin Resistance Antibodies	>110 publications with LEPR and Insulin Resistance
Necrosis Antibodies	>110 publications with LEPR and Necrosis
Immunologic Deficiency Syndromes Antibodies	>93 publications with LEPR and Immunologic Deficiency Syndromes

Organs/Tissues associated with LEPR elisa kit

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>13 publications with LEPR and Bone
Connective Tissue Antibodies	>4 publications with LEPR and Connective Tissue
Heart Antibodies	>3 publications with LEPR and Heart
Muscle Antibodies	>3 publications with LEPR and Muscle
Brain Antibodies	>3 publications with LEPR and Brain
Vascular Antibodies	>2 publications with LEPR and Vascular
Embryonic Tissue Antibodies	>2 publications with LEPR and Embryonic Tissue
Ear Antibodies	>1 publications with LEPR and Ear
Kidney Antibodies	>1 publications with LEPR and Kidney
Umbilical Cord Antibodies	>1 publications with LEPR and Umbilical Cord