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P-Selectin (P-SELECTIN/CD62P) ELISA Kit for Human

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS701631

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for P-selectin has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any P-selectin present is bound by… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
P-Selectin (P-Selectin/CD62P), ELISA Kit
Full Product Name
Human P-Selectin ELISA Kit
Product Gene Name
P-Selectin/CD62P elisa kit
Product Synonym Names
Human P-Selectin ELISA kit; P-Selectin
Species Reactivity
Human
Assay Type
Quantitative Sandwich
Samples
Serum, plasma and tissue homogenates
Detection Range
0.9 ng/ml-60 ng/ml
Sensitivity
< 0.225 ng/ml
Specificity
This assay has high sensitivity and excellent specificity for detection of human P-selectin. No significant cross-reactivity or interference between human P-selectin and analogues was observed.
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
Inter-assay Precision
Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
Molecular Weight
90,834 Da
OMIM
gene+601367
3D Structure
ModBase 3D Structure for P16109
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Typical Testing Data/Standard Curve (for reference only) of P-Selectin/CD62P elisa kit

Human P-SELECTIN/CD62P ELISA Kit – Cat# MBS701631

Other Notes

Small volumes of P-Selectin/CD62P elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for P-Selectin/CD62P purchase

MBS701631 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the P-Selectin (P-Selectin/CD62P) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing P-Selectin/CD62P. The ELISA analytical biochemical technique of the MBS701631 kit is based on P-Selectin/CD62P antibody-P-Selectin/CD62P antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect P-Selectin/CD62P antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, P-Selectin/CD62P. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Additional Details

NCBI/Uniprot data below describe general gene information for P-Selectin/CD62P. It may not necessarily be applicable to this product.

NCBI GI #
157419154
NCBI GeneID
6403
NCBI Accession #
NP_002996.2
UniProt Primary Accession #
P16109
UniProt Secondary Accession #
Q5R344; Q8IVD1
UniProt Related Accession #
P16109
GenBank Nucleotide #
NM_003005.3
NCBI Official Full Name
P-selectin
NCBI Official Synonym Full Names
selectin P (granule membrane protein 140kDa, antigen CD62)
NCBI Official Symbol
SELP
NCBI Official Synonym Symbols
CD62; GRMP; PSEL; CD62P; GMP140; LECAM3; PADGEM
UniProt Protein Name
P-selectin
UniProt Synonym Protein Names
CD62 antigen-like family member P; Granule membrane protein 140; GMP-140; Leukocyte-endothelial cell adhesion molecule 3; LECAM3; Platelet activation dependent granule-external membrane protein; PADGEM; CD_antigen: CD62P
Protein Family
P-selectin
UniProt Gene Name
SELP
UniProt Synonym Gene Names
GMRP; GRMP; GMP-140; LECAM3; PADGEM
UniProt Entry Name
LYAM3_HUMAN
NCBI Protein Information
P-selectin; GMP-140; granule membrane protein 140; granulocyte membrane protein; CD62 antigen-like family member P; platelet alpha-granule membrane protein; leukocyte-endothelial cell adhesion molecule 3; platelet activation dependent granule-external membrane protein

NCBI Summary for P-Selectin/CD62P

This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq, Jul 2008]
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UniProt Comments for P-Selectin/CD62P

Function: Ca2+-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1.1 PublicationManual assertion based on experiment in:Ref.7
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Research Articles on P-Selectin/CD62P

1. Individuals who undertake physical activity regularly, benefit from each single physical effort, because of decrease in serum concentration of proinflammatory molecules such as L-selectin and P-selectin.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with P-Selectin/CD62P elisa kit

 Reference Product  PubMed Publications
 CRP elisa kit  >8 publications with P-Selectin/CD62P and CRP
 ITGAM elisa kit  >6 publications with P-Selectin/CD62P and ITGAM
 SELPLG elisa kit  >5 publications with P-Selectin/CD62P and SELPLG
 ITGB2 elisa kit  >4 publications with P-Selectin/CD62P and ITGB2
 CD63 elisa kit  >3 publications with P-Selectin/CD62P and CD63
 STAT6 elisa kit  >2 publications with P-Selectin/CD62P and STAT6

Pathways associated with P-Selectin/CD62P elisa kit

 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 IL-3 Signaling Pathway antibodies  IL-3 Signaling Pathway Diagram
 IL4-mediated Signaling Events Pathway antibodies  IL4-mediated Signaling Events Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Platelet Activation, Signaling And Aggregation Pathway antibodies  Platelet Activation, Signaling And Aggregation Pathway Diagram
 Platelet Degranulation Pathway antibodies  Platelet Degranulation Pathway Diagram

Diseases associated with P-Selectin/CD62P elisa kit

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >69 publications with P-Selectin/CD62P and Cardiovascular Diseases
 Inflammation Antibodies  >36 publications with P-Selectin/CD62P and Inflammation
 Heart Diseases Antibodies  >30 publications with P-Selectin/CD62P and Heart Diseases
 Myocardial Ischemia Antibodies  >26 publications with P-Selectin/CD62P and Myocardial Ischemia
 Atherosclerosis Antibodies  >23 publications with P-Selectin/CD62P and Atherosclerosis
 Thrombosis Antibodies  >17 publications with P-Selectin/CD62P and Thrombosis
 Disease Models, Animal Antibodies  >12 publications with P-Selectin/CD62P and Disease Models, Animal
 Myocardial Infarction Antibodies  >11 publications with P-Selectin/CD62P and Myocardial Infarction
 Necrosis Antibodies  >9 publications with P-Selectin/CD62P and Necrosis
 Stroke Antibodies  >8 publications with P-Selectin/CD62P and Stroke

Organs/Tissues associated with P-Selectin/CD62P elisa kit

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >68 publications with P-Selectin/CD62P and Blood
 Vascular Antibodies  >30 publications with P-Selectin/CD62P and Vascular
 Brain Antibodies  >13 publications with P-Selectin/CD62P and Brain
 Muscle Antibodies  >8 publications with P-Selectin/CD62P and Muscle
 Lung Antibodies  >7 publications with P-Selectin/CD62P and Lung
 Kidney Antibodies  >5 publications with P-Selectin/CD62P and Kidney
 Bone Antibodies  >5 publications with P-Selectin/CD62P and Bone
 Testis Antibodies  >4 publications with P-Selectin/CD62P and Testis
 Eye Antibodies  >3 publications with P-Selectin/CD62P and Eye
 Nerve Antibodies  >3 publications with P-Selectin/CD62P and Nerve
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