Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor) (IL6ST) ELISA Kit for Mouse

Name: Mouse IL6ST ELISA Kit; MyBioSource
Brand: MyBioSource
SKU: MBS702730
Price: 295 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS702730

MBS702730 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the interleukin 6 signal transducer (gp130, oncostatin M receptor) (IL6ST) ELISA Kit target analytes in biological samples. The… More details

$295 / 24-Strip-Wells (LIMIT 1) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Request Current Manual

Product Overview

Online Datasheet in PDF

Product Name

interleukin 6 signal transducer (gp130, oncostatin M receptor) (IL6ST), ELISA Kit

Full Product Name

Mouse glucoprotein 130, gp130 ELISA Kit

Product Gene Name

IL6ST elisa kit

Product Synonym Names

Mouse glucoprotein 130; gp130 ELISA KIT; CD130; CDw130; GP130; GP130-RAPS; IL6R-beta; CD130 antigen; IL6ST nirs variant 3; OTTHUMP00000122545; gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form; gp130 transducer chain; int; interleukin 6 signal transducer (gp130; oncostatin M receptor)

Species Reactivity

Mouse

Specificity

This assay has high sensitivity and excellent specificity for detection of Mouse IL6ST. No significant cross-reactivity or interference between Mouse IL6ST and analogues was observed.

Preparation and Storage

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Intra-assay Precision

Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.

Molecular Weight

102,451 Da

3D Structure

ModBase 3D Structure for Q00560

Detection Wavelength

450 nm

Sample Volume

50-100ul

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of IL6ST elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL6ST. It may not necessarily be applicable to this product.

NCBI GI #

225007625

NCBI GeneID

16195

NCBI Accession #

NP_034690.3

UniProt Primary Accession #

Q00560

UniProt Secondary Accession #

G5E8D2

UniProt Related Accession #

Q00560

GenBank Nucleotide #

NM_010560.3

NCBI Official Full Name

interleukin-6 receptor subunit beta

NCBI Official Synonym Full Names

interleukin 6 signal transducer

NCBI Official Symbol

Il6st

NCBI Official Synonym Symbols

CD130; gp130; AA389424; BB405851; D13Ertd699e; 5133400A03Rik

UniProt Protein Name

Interleukin-6 receptor subunit beta

UniProt Synonym Protein Names

Interleukin-6 signal transducer; Membrane glycoprotein 130; gp130; Oncostatin-M receptor subunit alpha; CD_antigen: CD130

Protein Family

Interleukin-6 receptor

UniProt Gene Name

Il6st

UniProt Synonym Gene Names

IL-6 receptor subunit beta; IL-6R subunit beta; IL-6R-beta; IL-6RB; gp130

UniProt Entry Name

IL6RB_MOUSE

NCBI Protein Information

interleukin-6 receptor subunit beta; IL-6RB; IL-6R-beta; IL-6R subunit beta; membrane glycoprotein 130; IL-6 receptor subunit beta; interleukin-6 signal transducer; oncostatin-M receptor subunit alpha

UniProt Comments for IL6ST

Function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not bind IL6. May have a role in embryonic development.

Research Articles on IL6ST

1. GP130 and STAT3 are critical for uterine receptivity and implantation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IL6ST elisa kit

Reference Product	PubMed Publications
STAT3 elisa kit	>255 publications with IL6ST and STAT3
LIF elisa kit	>226 publications with IL6ST and LIF
OSM elisa kit	>176 publications with IL6ST and OSM
LIFR elisa kit	>115 publications with IL6ST and LIFR
CNTF elisa kit	>109 publications with IL6ST and CNTF
JAK1 elisa kit	>48 publications with IL6ST and JAK1
IL6 elisa kit	>32 publications with IL6ST and IL6
PTPN11 elisa kit	>32 publications with IL6ST and PTPN11
SOCS3 elisa kit	>30 publications with IL6ST and SOCS3
TYK2 elisa kit	>18 publications with IL6ST and TYK2

Pathways associated with IL6ST elisa kit

Products by Pathway	Pathway Diagram
Adipogenesis Pathway antibodies	Adipogenesis Pathway Diagram
Androgen Receptor Signaling Pathway antibodies	Androgen Receptor Signaling Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
ESC Pluripotency Pathways antibodies	ESC Pluripotency Pathways Diagram
IL-6 Signaling Pathway antibodies	IL-6 Signaling Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Interleukin-6 Signaling Pathway antibodies	Interleukin-6 Signaling Pathway Diagram
Jak-STAT Signaling Pathway antibodies	Jak-STAT Signaling Pathway Diagram

Diseases associated with IL6ST elisa kit

Disease Name	Pubmed Publications
Inflammation Antibodies	>112 publications with IL6ST and Inflammation
Cardiovascular Diseases Antibodies	>100 publications with IL6ST and Cardiovascular Diseases
Carcinoma Antibodies	>56 publications with IL6ST and Carcinoma
Nervous System Diseases Antibodies	>51 publications with IL6ST and Nervous System Diseases
Disease Models, Animal Antibodies	>50 publications with IL6ST and Disease Models, Animal
Heart Diseases Antibodies	>47 publications with IL6ST and Heart Diseases
Necrosis Antibodies	>43 publications with IL6ST and Necrosis
Liver Diseases Antibodies	>36 publications with IL6ST and Liver Diseases
Hypertrophy Antibodies	>30 publications with IL6ST and Hypertrophy
Arthritis, Rheumatoid Antibodies	>25 publications with IL6ST and Arthritis, Rheumatoid

Organs/Tissues associated with IL6ST elisa kit

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>211 publications with IL6ST and Blood
Liver Antibodies	>85 publications with IL6ST and Liver
Bone Antibodies	>79 publications with IL6ST and Bone
Brain Antibodies	>78 publications with IL6ST and Brain
Heart Antibodies	>71 publications with IL6ST and Heart
Bone Marrow Antibodies	>57 publications with IL6ST and Bone Marrow
Embryonic Tissue Antibodies	>33 publications with IL6ST and Embryonic Tissue
Lung Antibodies	>30 publications with IL6ST and Lung
Joint Antibodies	>17 publications with IL6ST and Joint
Kidney Antibodies	>16 publications with IL6ST and Kidney